Reconstituting the Human Thymus with Paola Bonfanti
Update: 2021-10-17
Description
In this conversation, Dr Paola Bonfanti joins us to discuss recent work done by her group to reconstitute the human thymus outside of the human body, using cultured cells and a scaffold.
We also discuss how the thymus develops, educates T cells, and how single-cell sequencing and spatial information are changing our understanding of the organ.
Paola trained as a doctor in Milan, before training as a stem cell scientist at institutes in California and Switzerland. She now leads a research group at the Crick Institute in London that investigates tissues such as the thymus, and the pancreas in the context of their stem cell and epithelial cell biology.
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