Repurposing loperamide to target glioma, metabolic reprogramming, liquid biopsies.

Update: 2021-01-02

Description

In this episode, recorded just before the New Year, I discuss recent news in brain cancer research.

This includes:

How the drug loperamide (brand name Imodium), induces cell death in glioblastoma cell lines and if this could have promise for real, human applications.

Metabolic reprogramming via inhibition of a key cancer metabolite- D-2-Hydroxyglutarate (D-2-HG).

Developments of liquid biopsies for glioma.

Comments

In Channel

Will ChatGPT pave the way for a new revolution in healthcare?

2023-01-3149:57

Investigating the metabolic phenotype of primary glioblastoma

2022-07-1312:46

Cannabinoids and cannabis based medicine - Mary Biles

2022-05-0101:22:38

Chelation therapy: Treating gadolinium retention- Dr. Richard Semelka

2022-03-3002:31:57

Dr Brent Wagner- Examining the safety of gadolinium based contrast agents.

2022-02-2301:08:26

Dr. Elena Gross- Migraine prevention and the therapeutic use of ketones.

2022-02-2001:00:36

Ep 15: Gemma Herbertson- Neuro Fronteirs and raising awareness of neuroplastic therapies.

2022-01-1601:10:10

Care Oncology Clinic- Repurposed drugs for cancer

2021-03-2901:56:02

Dr. Stuart Farrimond- Experiences of being a brain cancer survivor with a medical background

2021-03-0501:04:41

Lorlatinib shrinks rare brain tumour in child after the standard of care fails.

2021-01-1312:34

Repurposing loperamide to target glioma, metabolic reprogramming, liquid biopsies.

2021-01-0240:39

THGPP Episode 10: Meredith Moore- 15 year progression free survival of Glioblastoma Multiforme.

2020-09-1701:41:09

THGPP Episode 9: Isabella Cooper- Ketosis, insulin signalling and health

2020-08-2102:23:02

THGPP Episode 8: Dr Mithu Storoni- Managing stress and anxiety in the age of Covid-19.

2020-04-1001:08:58

THGPP Episode 7: Marty Kendall- Optimising Nutrition

2020-04-0601:31:25

THGPP Episode 6: Akbar Khan MD- The potential of DCA and off label drugs to treat cancer.

2020-02-0354:11

THGPP Episode 3: Tristan Haggard- What's going on with our food system?

2020-01-1301:36:57

THGPP Episode 5: Nathan Delack- Cancer clusters- What can we learn from McCullom Lake?

2020-01-1335:51

THGPP Episode 4: Brent Wagner MD- Gadolinium based contrast agents. Are they safe?

2019-12-1041:29

THGPP Episode 2: Pablo Kelly- Managing GBM when chemoradiation shows little efficacy.

2019-11-2501:25:02

00:00

Repurposing loperamide to target glioma, metabolic reprogramming, liquid biopsies.

#box-pro-ellipsis-176220141785997{-webkit-line-clamp:2;}Repurposing loperamide to target glioma, metabolic reprogramming, liquid biopsies.

Repurposing loperamide to target glioma, metabolic reprogramming, liquid biopsies.

Andrew Scarborough

Repurposing loperamide to target glioma, metabolic reprogramming, liquid biopsies.