DiscoverAutism (Audio)Rescuing Phenotypes in PTHS-Derived Brain Organoids with Alysson Muotri - Sanford Stem Cell Symposium 2022
Rescuing Phenotypes in PTHS-Derived Brain Organoids with Alysson Muotri - Sanford Stem Cell Symposium 2022

Rescuing Phenotypes in PTHS-Derived Brain Organoids with Alysson Muotri - Sanford Stem Cell Symposium 2022

Update: 2022-11-28
Share

Description

Alysson Muotri discusses modeling Pitt-Hopkins syndrome (PTHS) using stem cells and brain organoids. He shares how rescuing TCF4 expression with CRISPR-mediated epigenetic induction of AAV vector delivery provides a gateway for targeted therapeutics for PTHS and related conditions. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 38516]
Comments 
Top Podcasts
The Best New Comedy Podcast Right Now – June 2024The Best News Podcast Right Now – June 2024The Best New Business Podcast Right Now – June 2024The Best New Sports Podcast Right Now – June 2024The Best New True Crime Podcast Right Now – June 2024The Best New Joe Rogan Experience Podcast Right Now – June 20The Best New Dan Bongino Show Podcast Right Now – June 20The Best New Mark Levin Podcast – June 2024
In Channel
Western Lifestyle Harms Your Gut: Tips to Improve

Western Lifestyle Harms Your Gut: Tips to Improve

2024-08-0808:59

Clinical Implications of Sensory-Movement Differences in Autism

Clinical Implications of Sensory-Movement Differences in Autism

2024-06-1251:09

Community Support and Cognitive Science Help Non-Speaking Autistics Flourish

Community Support and Cognitive Science Help Non-Speaking Autistics Flourish

2024-06-0639:16

Human Connection and Autism Intervention

Human Connection and Autism Intervention

2024-01-2229:01

The Importance of Considering Diversity in Autism Research and Practice with Brian Boyd - Autism Tree Project Foundation Global Neurodiversity Conference 2023

The Importance of Considering Diversity in Autism Research and Practice with Brian Boyd - Autism Tree Project Foundation Global Neurodiversity Conference 2023

2024-01-0331:59

Siblings of Neurodiversity - Autism Tree Project Foundation Global Neurodiversity Conference 2023

Siblings of Neurodiversity - Autism Tree Project Foundation Global Neurodiversity Conference 2023

2023-12-2858:10

Rett Syndrome Patient-Derived Cortical Brain Organoids with Robert T. Fremeau Jr. - Autism Tree Project Foundation Global Neurodiversity Conference 2023

Rett Syndrome Patient-Derived Cortical Brain Organoids with Robert T. Fremeau Jr. - Autism Tree Project Foundation Global Neurodiversity Conference 2023

2023-12-2038:35

Decoding Autism: Unraveling Early Brain Development with Eric Courchesne - Autism Tree Project Foundation Global Neurodiversity Conference 2023

Decoding Autism: Unraveling Early Brain Development with Eric Courchesne - Autism Tree Project Foundation Global Neurodiversity Conference 2023

2023-12-1242:02

Neurodiverse Heroes - Autism Tree Project Foundation Global Neurodiversity Conference 2023

Neurodiverse Heroes - Autism Tree Project Foundation Global Neurodiversity Conference 2023

2023-12-0701:01:05

Eye-Tracking: The Future of Diagnostics Prognostics and Treatment Planning in Autism Spectrum Disorder (ASD) with Karen Pierce - Autism Tree Project Foundation Global Neurodiversity Conference 2023

Eye-Tracking: The Future of Diagnostics Prognostics and Treatment Planning in Autism Spectrum Disorder (ASD) with Karen Pierce - Autism Tree Project Foundation Global Neurodiversity Conference 2023

2023-12-0136:51

Neurodiversity in Literature: Towards Authentic Representation - Autism Tree Project Foundation Global Neurodiversity Conference 2023

Neurodiversity in Literature: Towards Authentic Representation - Autism Tree Project Foundation Global Neurodiversity Conference 2023

2023-11-2749:55

Autism: The Human Brain on a Continuum with Daniel Geschwind - Autism Tree Project Foundation Global Neurodiversity Conference 2023

Autism: The Human Brain on a Continuum with Daniel Geschwind - Autism Tree Project Foundation Global Neurodiversity Conference 2023

2023-11-2233:10

The Human Microbiome and Autism with Rob Knight - Autism Tree Project Foundation Global Neurodiversity Conference 2023

The Human Microbiome and Autism with Rob Knight - Autism Tree Project Foundation Global Neurodiversity Conference 2023

2023-11-1701:18:23

Studying the Brain Through the Lens of Neurodevelopmental Disorders with Gaia Novarino - Breaking News in Stem Cells

Studying the Brain Through the Lens of Neurodevelopmental Disorders with Gaia Novarino - Breaking News in Stem Cells

2023-06-0201:09:36

The Earliest Detection of Neurodevelopmental Derailment Leading to Autism is Now in Our Grasp with Elizabeth Torres - Autism Tree Global Neuroscience Conference 2022

The Earliest Detection of Neurodevelopmental Derailment Leading to Autism is Now in Our Grasp with Elizabeth Torres - Autism Tree Global Neuroscience Conference 2022

2022-12-2338:36

Autism in Hollywood - Autism Tree Global Neuroscience Conference 2022

Autism in Hollywood - Autism Tree Global Neuroscience Conference 2022

2022-12-1901:08:19

Autism at Work: Opening More Doors to Workers Who Are Neurodivergent - Autism Tree Global Neuroscience Conference 2022

Autism at Work: Opening More Doors to Workers Who Are Neurodivergent - Autism Tree Global Neuroscience Conference 2022

2022-12-1241:55

Autism Gaming and Attention with Leanne Chukoskie - Autism Tree Global Neuroscience Conference 2022

Autism Gaming and Attention with Leanne Chukoskie - Autism Tree Global Neuroscience Conference 2022

2022-12-0929:13

Does Cannabidiol Have a Role in the Treatment of Problem Behaviors in Autism? with Doris Trauner - Autism Tree Global Neuroscience Conference 2022

Does Cannabidiol Have a Role in the Treatment of Problem Behaviors in Autism? with Doris Trauner - Autism Tree Global Neuroscience Conference 2022

2022-12-0226:18

Rescuing Phenotypes in PTHS-Derived Brain Organoids with Alysson Muotri - Sanford Stem Cell Symposium 2022

Rescuing Phenotypes in PTHS-Derived Brain Organoids with Alysson Muotri - Sanford Stem Cell Symposium 2022

2022-11-2818:38

loading
Google Play
Download from Google Play
Castbox
Download from App Store
usUnited States
00:00
00:00
x

0.5x

0.8x

1.0x

1.25x

1.5x

2.0x

3.0x

Sleep Timer

Off

End of Episode

5 Minutes

10 Minutes

15 Minutes

30 Minutes

45 Minutes

60 Minutes

120 Minutes

Rescuing Phenotypes in PTHS-Derived Brain Organoids with Alysson Muotri - Sanford Stem Cell Symposium 2022

Rescuing Phenotypes in PTHS-Derived Brain Organoids with Alysson Muotri - Sanford Stem Cell Symposium 2022

UCTV: UC San Diego