In this episode, we will embark on an intellectual journey with the eminent Dr Guillem Mòdol Caballero from University College London as he navigates the world of neuroscience and sheds light on his pioneering work in peripheral nerve injuries and gene therapy. Peripheral nerve injury refers to damage or dysfunction of the nerves that lie outside the brain and spinal cord, which are part of the peripheral nervous system. This system is responsible for transmitting information between the brain and spinal cord and the rest of the body. Peripheral nerve injuries can result from a variety of causes, including trauma, surgery, compression, and certain medical conditions.

The impact of a peripheral nerve injury can range from mild and temporary to severe and long-lasting, affecting sensation, movement, and organ or gland function depending on the nerves involved. Symptoms may include numbness, pain, weakness, or paralysis in the affected area.

Our conversation peels back the layers of genetic mutations and their profound effects at the protein level, revealing the potential of gene therapy to alter the course of devastating neurodegenerative diseases. Dr. Model's insights not only underscore the importance of understanding these conditions from a molecular standpoint but also spark a beacon of hope for those affected by such relentless ailments.

If you have any questions, suggestions, or feedback, please contact at scipodchat@gmail.com

Disclaimer: This podcast is for informational purposes only, and SciPodChat is not intended to replace professional advice. Please note that the views, information, or opinions expressed during SciPodChat are solely those of the individuals involved, not any professional organization in which they are involved.

We Talk Science