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SIBO, Methylation & Histamine Intolerance: The gut-skin connection with Joanne Kennedy

SIBO, Methylation & Histamine Intolerance: The gut-skin connection with Joanne Kennedy

Update: 2024-05-16
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We're replaying an old favourite with the super knowledgeable and lovely Joanne Kennedy - the SIBO, MTHFR & Histamine Intolerance expert.


Joanne gives us a complete download of her brain to help us understand methylation and why this is such an important aspect to consider in clients presenting with histamine intolerance.


Within the skin, we can see histamine intolerance present in the form of rosacea, peri oral dermatitis, hives, eczema and acne.


Now there's a lot of hype around methylation and we can be quick to blame our gene expression such as MTHFR gene mutations as the cause of impaired methylation; but throughout this podcast we quickly turn the spotlight away from one genetic SNP and highlight the burden environmental exposures and gastrointestinal infections can have on methylation.


Specifically, we delve into the impacts of SIBO on methylation and how this can impact histamine intolerance. 


In this episode, Jacinta & Joanne discuss:



  • What is methylation

  • How much does MTHFR really impact methylation 

  • How to identify red flags in a clients presentation for further investigation

  • What markers to investigate to understand methylation status

  • Causes of high & low homocysteine 

  • Understanding SIBO and it's impact on methylation 

  • Methylation connection with histamine intolerance

  • The methylation, histamine, SIBO, skin and hormone connection  

  • Treatment strategies for supporting methylation 

  • Common errors made in supplementation for methylation 


You can learn more about Joanne below: 



  • Website: https://joannekennedy.com.au/

  • Instagram: @joannekennedynaturopath


Music by Wavecont, ⁠https://www.wavecont.com/free-download/⁠Licensed under creative commons Attribution-ShareAlike 4.0 International ⁠https://creativecommons.org/licenses/by-sa/4.0/⁠Music promoted by ⁠https://www.chosic.com/free-music/all/

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SIBO, Methylation & Histamine Intolerance: The gut-skin connection with Joanne Kennedy

SIBO, Methylation & Histamine Intolerance: The gut-skin connection with Joanne Kennedy

Jacinta Barbagallo