Can the Seattle Seahawks break their home losing streak against the San Francisco 49ers? Corbin Smith and Brian Peacock analyze the crucial matchups and strategic battles that will shape this NFC West clash. From Sam Darnold's impact on Seattle's offense to the 49ers' revamped defense, every angle is covered. The hosts dissect Nick Bosa's game-changing potential, Kyle Shanahan's offensive wizardry, and the importance of Christian McCaffrey in the run game. With both teams facing "a lot of familiarity, but a lot of unknowns," this preview offers essential insights for fans. Tune in for expert predictions and learn why red zone performance could be the key to victory in this season opener.

San Francisco 49ers fans are treated to daily news and analysis with Locked On 49ers, hosted by football analyst Brian Peacock and former NFL/AFL cornerback Eric Crocker.

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