Selecting Approaches for Hit Identification and Increasing Options by Building the Efficient Discovery of Actionable Chemical Matter from DNA-Encoded Libraries

Update: 2021-01-13

Description

Volume 25 Issue 2, February 2021

Podcast Editor Rob Howes chats with Marie-Claire Peakman, Ph.D. (Executive Director, Discovery Sciences, Pfizer), author of the featured paper "Selecting Approaches for Hit Identification and Increasing Options by Building the Efficient Discovery of Actionable Chemical Matter from DNA-Encoded Libraries" in the SLAS Discovery 2021 February Special Issue Hit Discovery Methodology with Guest Editors Mark Wigglesworth and Peter Hodder.

This Special Issue of SLAS Discovery presents the topic Hit Discovery Methodology which highlights the use of existing and progressive technologies in Hit Discovery and how these technologies may be combined to generate vital hits for drug discovery.

Comments

In Channel

Behind the Scenes at SLAS2023: Special Interview with Davide Gianni

2023-09-1308:32

Behind the Article: A Perspective on the Discovery of Enzyme Activators

2023-03-2909:45

New at SLAS: Protocols In Drug Discovery

2023-02-2212:57

Behind the Scenes at SLAS Europe: Special Interview with Jonathan Wingfield

2022-09-2112:25

Behind the Scenes at SLAS Europe: Special Interview with Timothy Spicer

2022-07-2015:21

Special Issue: 3D Cell Culture Approaches of Microphysiologically Relevant Models

2022-04-2715:31

SLAS Discovery x Assay Guidance Manual: Robust or Go Bust

2021-12-1519:32

Special Issue: Applications of Biophysics in Early Drug Discovery

2021-09-2214:03

Special Issue: Functional Genomics for Target Identification

2020-06-2313:14

Special Collection: Ion Channels and Relevant Drug Screening Approaches

2020-06-0106:21

Special Issue: Advances in Cellular Target Engagement and Target Deconvolution

2020-02-0121:59

Meet Editor-in-Chief Bob Campbell and SLAS Discovery!

2020-01-0111:08

In Conversation: SLAS Editors on Open Access

2021-10-2713:38

Approaches for Prioritizing High-Quality Chemical Matter in Chemical Probe and Drug Discovery

2021-08-1819:08

Special Issue: Advances in Protein Degradation

2021-06-3024:37

Selecting Approaches for Hit Identification and Increasing Options by Building the Efficient Discovery of Actionable Chemical Matter from DNA-Encoded Libraries

2021-01-1332:31

High-Throughput Screening for Drugs That Inhibit Papain-Like Protease in SARS-CoV-2

2020-11-1811:22

Comparison of Cell and Organoid-Level Analysis of Patient-Derived 3D Organoids to Evaluate Tumor Cell Growth Dynamics and Drug Response

2020-07-2307:53

00:00

Selecting Approaches for Hit Identification and Increasing Options by Building the Efficient Discovery of Actionable Chemical Matter from DNA-Encoded Libraries

#box-pro-ellipsis-176694229394071{-webkit-line-clamp:2;}Selecting Approaches for Hit Identification and Increasing Options by Building the Efficient Discovery of Actionable Chemical Matter from DNA-Encoded Libraries

Selecting Approaches for Hit Identification and Increasing Options by Building the Efficient Discovery of Actionable Chemical Matter from DNA-Encoded Libraries

Rob Howes, Ph.D.

Selecting Approaches for Hit Identification and Increasing Options by Building the Efficient Discovery of Actionable Chemical Matter from DNA-Encoded Libraries