Sub-typing ovarian cancer: Dr Charles Gourley – University of Edinburgh Cancer Research Center, UK
Update: 2012-11-19
Description
Previously thought to be one disease, ovarian cancer is now diagnosed as at least five different diseases based on the histology.
For predictive biomarkers to work properly they must predict the reaction of drug treatment within these subtypes and not the disease in general. In ovarian cancer, standard first line treat is very often effective, so evidence from biomarkers must be very strong to deviate from this standard.
Dr Gourley also discusses the move to a more personalised medicine and variations even in tumours within a single patient.
For predictive biomarkers to work properly they must predict the reaction of drug treatment within these subtypes and not the disease in general. In ovarian cancer, standard first line treat is very often effective, so evidence from biomarkers must be very strong to deviate from this standard.
Dr Gourley also discusses the move to a more personalised medicine and variations even in tumours within a single patient.
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