Summary: Fact Sheet – President Donald J. Trump Unveils the Genesis Mission1. What the Genesis Mission Is

• President Trump signs an Executive Order launching the Genesis Mission, a national effort to use AI to transform scientific research and speed up discovery.
• The Mission will:

Key implementation points:

• Secretary of Energy:
• Assistant to the President for Science and Technology (APST):
• Secretary of Energy, APST, and Special Advisor for AI & Crypto:
• Priority focus areas:

These are framed as the “greatest scientific challenges of our time” tied to national, economic, and health security.

• The fact sheet argues that despite rising research budgets since the 1990s, scientific progress has slowed:

  • Fewer new drug approvals,
  • More researchers needed for the same level of output.

• AI is presented as a force multiplier for science:

  • AI can:
  • Work that took years could now take weeks or months.

• To do this effectively, AI needs:

  • Large, high‑quality, well‑organized datasets, and
  • Significant computing power.

• The fact sheet emphasizes that:

  • These datasets and computing capabilities already exist within DOE National Laboratories.
  • The Genesis Mission brings AI to bear on this existing infrastructure, creating:

The Genesis Mission is framed as part of a larger AI strategy:

• January:
• April:
• July (two separate actions):
• July – America’s AI Action Plan:
• September:

2. Why AI + DOE: National Security & Economic Development3. Positioning Within Trump’s Broader AI Agenda