Synthetic Biology: DNA Recording and Computation
Description
What if we could see biology exactly where it happens — every gene, every molecule, every cell, in its true 3D environment?
In this podcast, we journey into the transformative world of spatial and 3D omics, where advanced molecular technologies and powerful computational tools allow scientists to map tissues, organs, and entire organisms with unprecedented detail.
Each episode explores cutting-edge innovations such as:
• spatial transcriptomics and single-cell 3D atlases
• volumetric DNA microscopy & in situ sequencing
• advanced imaging + sequencing hybrid platforms
• protein, chromatin, and metabolic spatial mapping
• computational pipelines for high-dimensional spatial data
• AI-driven reconstruction of tissues and cellular neighborhoods
• applications in cancer biology, neuroscience, immunity, and regenerative medicine
We break down both the technologies shaping the field and the computational challenges—including data integration, noise correction, multi-modal fusion, and building true 3D models of biological systems.
Perfect for biotech students, researchers, and anyone fascinated by the future of molecular biology, this podcast reveals how spatial omics is transforming our understanding of disease, development, and the architecture of life itself.




