The sermon meticulously defends the biblical foundation of the canon, asserting its divine origin and rejecting claims that the Roman Catholic Church arbitrarily determined its contents. It emphasizes that the canon is a divinely inspired and authoritative standard for faith and practice, rejecting humanist interpretations and highlighting the importance of presuppositional apologetics. Drawing from historical confessions and scriptural passages, the sermon underscores that the Bible's authority stems from God's revelation, not human tradition, and that recognizing this truth is essential for understanding and applying God's word to all aspects of life.