The Changing Landscape of Rectal Cancer Treatment
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Dr. Goldfarb, your request led us to this deep dive into the evolving treatment landscape of rectal cancer. In this episode of Ask Curie, we explore non-operative management strategies, the role of immunotherapy, and how biomarker-driven care is transforming clinical decision-making. We break down key findings, including the growing viability of the “watch-and-wait” approach, short-course vs. long-course radiation therapy, and emerging targeted therapies like checkpoint inhibitors for MSI-high tumors. Should oncologists be reconsidering surgery-first approaches? And what does the latest data say about de-escalating treatment without compromising outcomes? Tune in for an evidence-based look at the future of rectal cancer treatment.












