I talk with Michael Strevens about the scientific enterprise. Does science get at objective truth or is it limited by subjective world-views? We begin by discussing the roles of Kuhn and Popper in the "Great Method Debate", before going on to discuss developments in the sociology of science, by figures such as Bruno Latour, who showed that there is actually quite a bit of subjectivity in everyday scientific activities. We then go on to discuss Michael's contribution to this debate and we examine the "Iron Rule of Explanation". We look at the constellation of ideas that buttress the Iron Rule of Explanation and examine their suitability to the scientific enterprise. Finally, we consider the role that beauty can play in science.