Welcome to season two of Kicking Gout in the Acid. This season will dive into additional topics of importance to not only those with gout, but for those treating the disease as well. Whether you’ve been recently diagnosed, care for someone suffering, or are a medical professional treating the disease, the Kicking Gout in the Acid podcast can help you learn more.







This episode of Kicking Gout in the Acid features a conversation between Dr. Larry Edwards and Dr. Richard Johnson, board-certified nephrologist and member of the Board of Directors for the Gout Education Society. The two explore the connection between gout and kidney health through topics like uric acid regulation through the kidneys, treatment options, and considerations for medical professionals in charge of care should keep in mind.







Key Takeaways:









The kidneys play a central role in uric acid regulation. About two-thirds of uric acid is excreted by the kidneys, and one-third by the gut. When kidney function declines, uric acid retention occurs, increasing gout risk.







Kidney disease and gout are closely linked to one another. Chronic kidney disease (CKD) is a major cause of gout because impaired kidney function leads to uric acid buildup. Conversely, high uric acid may contribute to CKD progression, creating a vicious cycle.







In those with kidney disease, treatment can look a bit different. Notably, NSAIDs may not be an option due to their harmful impact on the kidneys. For those with kidney disease looking for pain relief from a gout flare, options like steroids should be considered. Also, historical dosing restrictions for allopurinol in CKD have led to undertreatment, but recent evidence supports gradual titration to higher doses when monitored.







For medical professionals, it’s important to screen those with gout for kidney disease and vice versa. Medications known to raise uric acid should also be reviewed, namely, diuretics. Comorbidities should always be considered when treating gout.









Start your journey with gout today via the Gout Education Society website and sign up for the monthly newsletter.







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Looking for nearby gout specialists? Find rheumatologists, nephrologists and more via the Gout Specialists Network.







Educational Materials:









Gout Patient Brochure







Medical Professional Guide







Crystal Clear Checklist









Kicking Gout in the Acid is sponsored by Sobi.