Canto Divina: Singing Psalms for Transformation is based upon the process of Lectio Divina and adds the gift of sacred music and the baptism of the holy spirit for transformation. This work strategically develops the research on music and medicine and the connection to Catholicism. Deborah presents her education, experience, and personal transformation through the music of our faith and supports this information with a summary of the history and science of music and medicine. The process of Canto Divina is then defined and practiced with appropriate examples to model this transformation. The psalms were chosen for this process of transformation as they clearly reflect the emotional connection to the heart of God through the words of King David. In this work the research and application of music and medicine has been fully integrated with Catholicism while providing a new intervention for transformation. As St. Augustine once noted, when we sing, we pray twice.