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The invisible battle behind RNA delivery

The invisible battle behind RNA delivery

Update: 2025-12-02
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A new study using advanced microscopy techniques has revealed why lipid nanoparticles (LNPs), used to deliver RNA in vaccines and gene therapies, often fail to deliver their cargo effectively inside cells. Researchers discovered that lipids and RNA often separate inside cells, and the cell's repair system actively hinders RNA escape, limiting therapeutic efficacy. Understanding these barriers is crucial for designing more effective RNA delivery systems.

Read the full article at https://www.paperleap.com/blog/articles/the-invisible-battle-behind-rna-delivery-0cccua
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The invisible battle behind RNA delivery

The invisible battle behind RNA delivery

Paperleap