In this special episode of On the Edge of Breakthrough, recorded live at the 2025 ASCO Annual Meeting, host Dr. Monty Pal sits down with two of City of Hope’s newest clinical leaders: Dr. Walter Stadler, Chief Clinical Officer at City of Hope Chicago, and Dr. Alan Bryce, Chief Clinical Officer at Hope Phoenix.

Together, they explore what it takes to build a national model for research-driven care, from creating system-wide infrastructure for precision medicine to integrating AI across core services like  pathology, real-time cross-network collaboration, and genomic innovation throughout  40+ sites. The episode dives into the growing complexity of cancer treatment, the burden on individual providers, and how building smarter systems can accelerate access to trials, for all  communities.

The discussion touches on simplifying clinical trial design, rethinking dose strategies, and the institutional commitment to pushing forward both early detection and long-term survivorship.

If you're interested in where oncology is headed next—from both a research and systems perspective—this episode is a must-listen.

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Presented by City Of Hope
www.CityOfHope.org