Mitrix Bio

Website:
https://www.mitrix.bio/

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Show notes:


Personal introduction:

Bioreactor-grown mitochondria

8-9 years old field

Grow young healthy mitochondrial and transplant them into the cells




Had a few software companies on the 1990’s and fusion start-ups

Stanford accelerator


Lasers

Molecular and biological imaging

Mito-field is booming

The mechanisms of the mitochondria than the biologics of them

Gas turbines Little rotating turbines

Combust fuel and oxygen

That does anything to power the cell



The main question:
What is aging?

Aging is healing, and the loss of the ability to heal

The body and cells are not static

There is enough rebuilding capacity when you are young

As you age, the energy available to rebuild your cells slacks off

They can’t replicate as fast

Your body can’t afford to maintain large muscles so they shrink

“We have made older animals younger…”

They just need the higher levels of energy that is lost after youth



The theory: texting and repairing mechanisms weaken and don’t have enough energy to do their jobs as effectively

The brain and heart don’t decline as fast as the rest of the body

The kidneys and skin and muscles decline the fastest

Mitochondria are fundamental to all of your cells and organs and muscles

10% of you body weight and generate 90% of your energy in your body

Merged a billion years ago with simple-celled organisms




Mitochondrial dna


You start with One nuclear dna and 500,000 mtDNA

26 major groups of mtDNA


As you age the dna acquires copying errors like a computer disk that needs to be cleaned up

Mitochondrial energy decline IS aging

Hallmarks of aging : Both nuclear dna and mtDNA are decaying and declining

You have to replace a car battery, and we should be able to do the same thing with ourselves: the body and car can just keep going….

The cells will scoop up the new mitochondria and use the new fresh free mitochondria

75 years old, you can feel 40-45 years old again

Skin will get tighter and muscles will regrow




Reversing aging and not just slowing it down

Starting with the longevity market / field

Most of it is fluff and noise and bubbles that pop

We have a bubble because there’s a huge opportunity and a lot of people dive in

A lot of billionaires investing

Altos Laboratories from Jeff Bezos, Amazon

Retro.bio by Sam Altman /Open Ai, ChatGPT

New Limit from Brian Armstrong, coinbase

Hevolution Project by Saudi Arabia





One or two good approaches:

Mitochondria transplants

Epigentic reprogramming. Future biogenetic mitochondria producing machines in every house as a daily treatment/supplement

Holy Fire book

Correlation vs causation

Secondary and tertiary effects

Mitochondria is a primary cause of aging

Telomere is secondary or just correlary effect

“Allow aging to happen” as a compromise that’s a trade off

Famine and intermittent fasting vs caloric restriction

The body uses the muscles to funnel to the heart and brain

Intermittent feasting

Saunas are recommended

There are a lot of excesses in the longevity field

Lots of vitamins

Lots of running

More is not always better

Minimum effective dose

Maximum effective dose

Homeostasis