DiscoverHuman 3 with Brom and SamTop 10 Human 3 startups - brain implants, concierge longevity medicine, designer psychedelics and more
Top 10 Human 3 startups - brain implants, concierge longevity medicine, designer psychedelics and more

Top 10 Human 3 startups - brain implants, concierge longevity medicine, designer psychedelics and more

Update: 2025-05-15
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Brom Rector and Sam Tabone from XEIA get specific on what Human 3 actually looks like in practice by analyzing 10 startups through the Human 3 lens.


We analyze the companies on the 5 pillars of Human 3


  • Distribution shifting potential - can this company elevate the already healthy in addition to healing the sick?
  • HERO - is the company inspired by Historical Examples of Real-world Outcomes
  • Step Change potential - if this thing works, will it be an order of magnitude better than the standard of care?
  • Endogenous Accelerant - does the company have a built in flywheel?
  • X-disciplinarity - does the innovation happen at the intersection of multiple disciplines?



Timestamps and companies mentioned:


0:00 - what defines a Human 3 startup?


16:00 - Mindstate Design Labs: AI designed psychedelic therapies


25:00 - Kadence Bio: treatment for premature ejaculation


34:20 - NeuroBionics: minimally invasive deep brain stimulation for Parkinson's


42:00 - Motif Neurotech: minimally invasive TMS for depression


51:45 - Xylo Bio: non-hallucinogenic psychedelics


1:01:45 - Pangea Bio: AI to identify natures hidden cures


1:11:00 - Kerna Labs: AI model to unlock the therapeutic potential of mRNA


1:20:00 - Superpower: concierge longevity medicine on your iPhone


1:30:00 - Coherence: closed loop neuromodulation to treat brain cancer (Glioblastoma)


1:40:27 - Beond: treating Opiate addiction with Ibogaine


1:52:00 - closing thoughts

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Top 10 Human 3 startups - brain implants, concierge longevity medicine, designer psychedelics and more

Top 10 Human 3 startups - brain implants, concierge longevity medicine, designer psychedelics and more

Brom Rector and Sam Tabone