When Tramadol hit the market, it was hailed as the miracle middle ground. A safer opioid that could ease chronic pain without the addictive risks of morphine or hydrocodone. Doctors prescribed it widely, pharmacists trusted it, and patients finally felt like there was something they could take long-term without fear.

But now, a new British Medical Journal study has revealed a very different story. For chronic pain, Tramadol barely outperforms a placebo, and worse, in many cases, it causes more harm than relief. 

What once looked like a gentler alternative is now revealing a more complicated story, one that has less to do with strength and more to do with how this drug interacts with your body over time.

Because the truth is, pain isn't just a signal to suppress; it's a system your body built to protect you. When that system gets out of balance, it can amplify even the smallest discomfort into chronic suffering. And while medication can help short term, it rarely teaches the body how to reset itself. Understanding that difference is the key to real, lasting relief.

So what do you do when the medicine that's supposed to help starts making you feel worse? 

In this episode, I break down what this new research means for long-term pain management, why Tramadol may not be the "safe opioid" we were promised, and how to start your own pain reset.

Things You'll Learn In This Episode 

The myth of the "safe" opioid
Tramadol was once seen as a breakthrough for chronic pain, but what does the latest research reveal about why it may actually work against long-term healing?

The pain system, explained
Pain isn't your enemy; it's your body's alarm system. What happens when that system gets stuck in the "on" position, and how do you turn it back down?

Why medications lose their power over time
If painkillers stop working, does it mean your body is failing or that your nervous system has adapted in ways you can reverse?

How to reset pain naturally
From movement and sleep to supplements and low-dose naltrexone, what small, daily changes can help you calm your pain system and finally feel relief?

About Your Host

Steve Hoffart is an award-winning pharmacist, entrepreneur, speaker, and podcaster. As the visionary founder of Magnolia Pharmacy, Steve saw a need for a more personal pharmacy that could make a bigger impact. Today, Steve and his team of experts deliver on that promise, working with patients and their physicians to solve medication problems and offer personalized solutions to achieve better health and wellness. As host of The Trusted Pharmacist podcast and through his combined reach of over 250,000 on social media, Steve shares actionable advice on nutrition, supplements, and wellness strategies while advocating for meaningful change in healthcare.