Trans 101: How Transgender Hormone Therapy Changes Body and Brain
Update: 2025-10-16
Description
(00:00:00 ) Trans 101: How Transgender Hormone Therapy Changes Body and Brain
(00:03:26 ) Why you can't change the mind
(00:05:17 ) Estrogen and what it takes to start it
(00:08:58 ) Testosterone and what it takes to start it
(00:11:58 ) How hormones work
(00:15:19 ) Psychological changes
(00:19:48 ) Physical changes on estrogen
(00:21:31 ) Physical changes on testosterone
(00:22:53 ) Surgical options for trans women
(00:26:28 ) Surgical options for trans men
(00:32:01 ) Conclusion
(00:33:17 ) Outro
For decades, doctors tried to psychoanalyze trans people out of being trans. Spoiler: it didn't work. This episode dives into the medical reality of gender transition—from how hormones actually work at the cellular level to the emotional rollercoaster of a second puberty. You'll learn what estrogen and testosterone really do to the body, what bottom growth actually means, and how modern surgery can create everything from boobs to fully functional penises with hydraulic erections. We cover the psychological shifts, the physical changes, the hilarious terminology trans people have coined, and why medical transition isn't about "fixing" anyone—it's about letting people finally be themselves.
More from Michelle Forcier:
More from Riley Black:
More from Charlie James:
Need music for a project? Use my Epidemic Sound referral link: https://share.epidemicsound.com/kbva2h
Connect with the show:
(00:03:26 ) Why you can't change the mind
(00:05:17 ) Estrogen and what it takes to start it
(00:08:58 ) Testosterone and what it takes to start it
(00:11:58 ) How hormones work
(00:15:19 ) Psychological changes
(00:19:48 ) Physical changes on estrogen
(00:21:31 ) Physical changes on testosterone
(00:22:53 ) Surgical options for trans women
(00:26:28 ) Surgical options for trans men
(00:32:01 ) Conclusion
(00:33:17 ) Outro
For decades, doctors tried to psychoanalyze trans people out of being trans. Spoiler: it didn't work. This episode dives into the medical reality of gender transition—from how hormones actually work at the cellular level to the emotional rollercoaster of a second puberty. You'll learn what estrogen and testosterone really do to the body, what bottom growth actually means, and how modern surgery can create everything from boobs to fully functional penises with hydraulic erections. We cover the psychological shifts, the physical changes, the hilarious terminology trans people have coined, and why medical transition isn't about "fixing" anyone—it's about letting people finally be themselves.
More from Michelle Forcier:
More from Riley Black:
- Website
- Order her latest book, The Last Days of the Dinosaurs
- Bluesky
More from Charlie James:
- Website
- Order his book, I’m Just a Little Guy: How to Escape the Horrors and Get Back to Dillydallying
- TikTok
Need music for a project? Use my Epidemic Sound referral link: https://share.epidemicsound.com/kbva2h
Connect with the show:
- Join the Patreon: https://patreon.com/tabooscience
- Leave me a voice memo: https://podline.fm/tabooscience
- Instagram: https://www.instagram.com/tabooscience
- YouTube: https://www.youtube.com/@tabooscience
- Website: https://www.tabooscience.show/
Comments
In Channel






















