DiscoverPsychopharmacology and Psychiatry UpdatesTrazodone vs. Doxepin vs. Melatonin: Comparing Alternatives for Sleep
Trazodone vs. Doxepin vs. Melatonin: Comparing Alternatives for Sleep

Trazodone vs. Doxepin vs. Melatonin: Comparing Alternatives for Sleep

Update: 2025-11-07
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In this episode, we explore a head-to-head comparison of trazodone, doxepin, and melatonin for treating insomnia when benzodiazepines are off the table. Which non-benzodiazepine sleep aid offers the best balance of effectiveness and tolerability in real-world psychiatric patients?

Faculty: Paul Zarkowski, M.D.
Host: Richard Seeber, M.D.

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Trazodone vs. Doxepin vs. Melatonin: Comparing Alternatives for Sleep

Trazodone vs. Doxepin vs. Melatonin: Comparing Alternatives for Sleep