The New Orleans Saints are in position as the San Francisco 49ers face a quarterback conundrum. Brock Purdy's injury opens the door for Mac Jones to potentially start. Kyle Shanahan's offense adapts, with Christian McCaffrey and Ricky Pearsall poised for increased roles against the  Saints.

Brandon Staley's insider knowledge as Saints' defensive coordinator adds intrigue to key matchups. The trenches take center stage as both teams emphasize the run game. Christian McCaffrey's workload and Alvin Kamara's impact loom large.

BECOME A LOCKED ON SAINTS INSIDER: https://joinsubtext.com/lockedonsaints

Follow & Subscribe on all Podcast platforms…

🎧https://lockedonpodcasts.com/podcasts/locked-on-saints/

Locked On NFL League-Wide: Every Team, Fantasy, Draft & More

🎧https://lockedonpodcasts.com/podcasts/locked-on-nfl/

LouisianaSports.Net's Ross Jackson hosts the Locked On Saints Podcast keeping the Who Dat Nation up-to-date with everything you need to know about your beloved New Orleans Saints.

And follow Ross on Twitter, where he’ll be sharing the latest news about the New Orleans Saints and talking with fans.

On Twitter:  https://twitter.com/RossJacksonNOLA

Support Us By Supporting Our Sponsors!

5-Hour ENERGY

Tee up that trip! Enter for a chance to win a dream golf trip for two to any golf tournament* in the USA. Visit https://5HEWIN.com for full rules and entry. No purchase necessary. Excludes the Master’s tournament. Ends October 31, 2025.

DoorDash

With DoorDash Streaks, you save every Saturday you order — stack it up all season and you could save up to $250. Order this Saturday. Keep the streak alive. Fuel your gameday — only with DoorDash. Terms apply. Promo period through 11/18.

Monarch Money

Take control of your finances with Monarch Money. Use code LOCKEDONNFL at monarchmoney.com/lockedonnfl for 50% off your first year.

Upside

Don’t let this offer drive on by, download the free Upside app now using my limited time promo code TOUCHDOWN for a limited time 25 cent per gallon bonus! Offers vary by user and location, Go to upside.com for terms and conditions.

Click Here to download the app: https://getupside.onelink.me/zlLr?af_xp=custom&pid=barrington&c=barrington_lockedon25&deep_link_value=promo&deep_link_sub1=lockedon25&af_dp=upsideapp%3A%2F%2F

Yahoo Fantasy

Presented by YahooFantasy #YahooPartner. Draft now at https://yahoofantasy.com/lockedonnfl.

PrizePicks

Download the PrizePicks app today and use code LOCKEDONNFL to get $50 in lineups after you play your first $5 lineup.

Gametime

Download the Gametime app, create an account, and use code LOCKEDONNFL for $20 off your first purchase. Terms apply. Download Gametime today. What time is it? Gametime.

FanDuel

Right now, new customers can bet just FIVE dollars and if your bet wins—you’ll get THREE HUNDRED dollars in bonus bets to use across the app.

FANDUEL DISCLAIMER: 21+ in select states. First online real money wager only. Bonus issued as nonwithdrawable free bets that expires in 14 days. Restrictions apply. See terms at sportsbook.fanduel.com. Gambling Problem? Call 1-800-GAMBLER or visit FanDuel.com/RG (CO, IA, MD, MI, NJ, PA, IL, VA, WV), 1-800-NEXT-STEP or text NEXTSTEP to 53342 (AZ), 1-888-789-7777 or visit ccpg.org/chat (CT), 1-800-9-WITH-IT (IN), 1-800-522-4700 (WY, KS) or visit ksgamblinghelp.com (KS), 1-877-770-STOP (LA), 1-877-8-HOPENY or text HOPENY (467369) (NY), TN REDLINE 1-800-889-9789 (TN)