While BYU enters this weekend's game in Boulder as a top-25 team and a 6.5-point favorite, there are a number of factors that could lead to a Colorado upset. For the Buffaloes to pull it off, they will need to execute on a few key fronts.

1. Kaidon Salter's Continued Improvement

Colorado's hopes for an upset start with quarterback Kaidon Salter. After a shaky start to the season, he was benched in Week 3, but he rebounded with his best performance of the year in a win over Wyoming. His ability to use both his arm and his legs was on full display. For Colorado to upset BYU, Salter will need to be at his best, protecting the ball and being a threat in the running game to open up the offense.

2. Take Advantage of BYU's Inexperience

BYU is led by true freshman quarterback Bear Bachmeier, who, while impressive in his first three starts, has yet to face a truly disruptive, blitz-heavy defense on the road in a hostile environment. Colorado's defense, led by its talented linebackers and safety Tawfiq Byard, will need to create pressure and force Bachmeier into making mistakes. If they can force turnovers and short-circuit BYU's offense, they can control the tempo of the game.

3. Establish the Run Game

To control the clock and keep BYU's explosive offense off the field, Colorado will need to establish the run game. Running backs Micah Welch and Simeon Price, both with over 140 rushing yards on the season, will be crucial. BYU's defense has been stellar, but if Colorado can wear them down in the trenches, it could open up play-action passing and tire out the Cougars' defensive front in the high altitude of Boulder.

4. Special Teams and Turnovers

Upset victories often hinge on the little things, and for Colorado, that means winning the turnover and special teams battle. BYU's defense has been opportunistic, forcing multiple turnovers in its last win, including a pick-six. Colorado cannot afford to give away free points or give BYU's offense a short field. If the Buffaloes can force a turnover or two and win the field position battle, they can put themselves in a position to win a low-scoring game.