In this AHA PAD initiative podcast, we will provide an overview of the epidemiology, risk factors, diagnosis, and management of PAD using a patient’s experience to illustrate critical points in the clinical journey.  Clinical pearls for differentiating different etiologies for common presentations of PAD such as limb discomfort and ulceration will be emphasized.  The importance of a team-based approach to diagnosis, treatment, and follow-up will also be highlighted.