In this episode, Dr. Morgentaler and Dr. Brandon talk about how testosterone can, in the right patients, be an effective solo treatment for erectile dysfunction despite common medical guidelines saying otherwise.

00:06 Testosterone and Erectile Dysfunction: The Debate – They kick things off by questioning the common belief that testosterone alone can’t fix ED.

00:54 Understanding the Traverse Study – They break down why a big study seemed to show testosterone doesn’t help erections—and why its results are misleading.

03:20 The Role of Testosterone in Erections – They explain how testosterone, nerves, and blood flow all have to work together for healthy erections.

08:59 Clinical Insights and Patient Experiences – Dr. Morgentaler shares real-world stories of men whose ED improved dramatically once their testosterone levels were restored.

19:43 Conclusion and Final Thoughts – They wrap up by stressing that while guidelines matter, treating each patient as an individual is the real key.

Resources -
TRAVERSE Study
Bhasin, S., Snyder, P. J., Cunningham, G. R., Matsumoto, A. M., Stephens-Shields, A. J., Cauley, J. A., Gill, T. M., Barrett-Connor, E., Swerdloff, R. S., Wang, C., Ensrud, K. E., Lewis, C. E., Budoff, M. J., Cohen, B., Pahor, M., Kenny, A. M., & Ellenberg, S. S. (2023). Cardiovascular safety of testosterone-replacement therapy. The New England Journal of Medicine, 389(2), 107–117. https://doi.org/10.1056/NEJMoa2215025

The Testosterone Trials (2016)
Snyder, P. J., Bhasin, S., Cunningham, G. R., Matsumoto, A. M., Stephens-Shields, A. J., Cauley, J. A., Gill, T. M., Barrett-Connor, E., Swerdloff, R. S., Wang, C., Ensrud, K. E., Lewis, C. E., Hou, X., Hou, X., Budoff, M. J., Ellenberg, S. S., & The Testosterone Trials Investigators. (2016). Effects of testosterone treatment in older men. The New England Journal of Medicine, 374(7), 611–624. https://doi.org/10.1056/NEJMoa1506119

2018 American Urological Association Guidelines on Erectile Dysfunction
Burnett, A. L., Nehra, A., Breau, R. H., Culkin, D. J., Faraday, M. M., Hakim, L. S., Heidelbaugh, J. J., Khera, M., Kirkby, E., McVary, K. T., Miner, M. M., Nelson, C. J., Sadovsky, R., Seftel, A. D., Shindel, A. W., & SOP Committee. (2018). Erectile dysfunction: AUA guideline. The Journal of Urology, 200(3), 633–641. https://doi.org/10.1016/j.juro.2018.05.004

With Dr. Abraham Morgentaler and Dr. Marianne Brandon

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