In this episode, Dr. Scott Sperling and early career leader, Dr. Zachary Resch, will be discussing the paper, Signs and Symptoms Method in Neuropsychology: A Standardized Observational Examination of Cognitive Functions Can Be Effective in Detecting Mild Cognitive Impairment, with two of the study authors, Dr. Carlo Abbate & Dr. Alessia Gallucci. In their study, the authors examined the diagnostic sensitivity and specificity of what they term the "NeuroPsychological Examination" or "NPE", which is a systematic method of collecting and quantifying cognitive and behavioral symptoms during a clinical interview. The NPE was implemented for 475 participants (208 with MCI, 188 with dementia, and 79 with subjective cognitive decline). Results demonstrated that the number of neuropsychological signs from the NPE could discriminate between all three groups with good sensitivity and specificity, which highlights its utility for clinical neuropsychologists.