This podcast episode features a conversation between Dr Oli Flower and his AI co-host, Simon (ChatGPT 4o), focusing on vasospasm and delayed cerebral ischemia (DCI) in aneurysmal subarachnoid haemorrhage (aSAH). The discussion covers:

• The distinction between radiological vasospasm (imaging finding) and DCI (clinical syndrome).
• The evolution of understanding DCI’s multifactorial causes, beyond just vasospasm.
• Evidence and controversies around ICU management, including blood pressure targets, nimodipine use, and the role of other interventions.
• Screening and monitoring strategies: transcranial Doppler, CTA, CTP, and the limitations of each.
• Post-management assessment, therapeutic hypertension, and the emerging role of milrinone.
• The importance of multimodal monitoring and the future potential of AI and global data sharing.
• The episode closes with a lighthearted off-topic discussion about casting for the new Naked Gun movie.

The conversation is rich in clinical nuance, highlights current evidence gaps, and emphasises the need for individualised patient care and ongoing research.