Dr. Selk interviews Dr. Mario Preti, a gynecologist and oncologist in Torino, Italy and the past President of the International Society for the Study of Vulvovaginal Disease (ISSVD), about vulvar cancer. Topics covered include prevalence, demographics, types of vulvar cancer, risk factors and causes, how vulvar cancer patients present, what is seen on physical exam, diagnosis, how to biopsy a suspicious lesion, treatment, impact of lymph node metastases, inguinal lymph node removal and sentinel node dissection, treating advanced vulvar cancer, when to recommend radiation therapy, prognosis, recurrence, treating recurrent disease, prevention of vulvar cancer, supportive care and the importance of patient awareness.