This scientific paper describes the sequencing, assembly, and genome analysis of the Mexican axolotl (Ambystoma mexicanum), a species of salamander known for its ability to regenerate. The researchers found that the axolotl genome is ten times larger than the human genome, mainly due to the expansion of long-termination repeat (LTR) retroelements. In addition, they found that the Pax3 gene, which is essential for tissue development in other vertebrates, is absent from the axolotl genome. Through gene-editing experiments, they showed that the axolotl's Pax7 gene has taken over the functions of Pax3. The article provides a valuable source of information for understanding genome evolution, regeneration mechanisms, and developmental processes in axolotls.

Nowoshilow, S., Schloissnig, S., Fei, J.-F. et al. El genoma del ajolote y la evolución de los reguladores clave de la ormación de tejidos. Nature 554,
50–57 (2018). https://doi.org/10.1038/nature25458