DiscoverScience on Player FMWhat Do We Know About SSRI Antidepressant Withdrawal? - Science Friday
What Do We Know About SSRI Antidepressant Withdrawal? - Science Friday

What Do We Know About SSRI Antidepressant Withdrawal? - Science Friday

Update: 2025-10-02
Share

Description

Roughly 1 in 10 Americans take antidepressants. The most common type is SSRIs, or  selective serotonin re-uptake inhibitors, like Prozac, Lexapro, and Zoloft. But what happens when you stop taking them? Studies don’t point to a single conclusion, and there’s ongoing debate among physicians and patients about the severity and significance of SSRI withdrawal symptoms. The discourse reached a fever pitch when Health Secretary Robert F. Kennedy Jr. compared SSRI withdrawal to heroin withdrawal in January.

Host Flora Lichtman digs into the data on SSRI withdrawal with psychiatrists Awais Aftab and Mark Horowitz.

Guests: Dr. Awais Aftab is a clinical associate professor of psychiatry at Case Western Reserve University.
Dr. Mark Horowitz is a clinical research fellow in the UK’s National Health Service and  scientific co-founder of Outro Health.

Transcripts for each episode are available within 1-3 days at sciencefriday.com.

 


Subscribe to this podcast. Plus, to stay updated on all things science, sign up for Science Friday's newsletters.

Comments 
In Channel
loading
00:00
00:00
x

0.5x

0.8x

1.0x

1.25x

1.5x

2.0x

3.0x

Sleep Timer

Off

End of Episode

5 Minutes

10 Minutes

15 Minutes

30 Minutes

45 Minutes

60 Minutes

120 Minutes

What Do We Know About SSRI Antidepressant Withdrawal? - Science Friday

What Do We Know About SSRI Antidepressant Withdrawal? - Science Friday