Though most engineering and technical works of ALMA occur during the daytime, astronomical observations can run day and night since the telescope is sensible to radio waves, which do not interfere with daylight. But how does the observatory operate 24/7? In this episode, James Miley, an ALMA Fellow who has worked as an astronomer on duty, will explain to us how they constantly monitor all weather conditions to achieve the best possible samples of the Universe through the instrumentation of ALMA. Let's discover how the two control rooms of the observatory operate to analyze 24/7 under constantly changing weather conditions.