DiscoverFunctional FlavorWhy Most Probiotics Don’t Work (And What to Do Instead) - Dr Colleen Cutcliffe
Why Most Probiotics Don’t Work (And What to Do Instead) - Dr Colleen Cutcliffe

Why Most Probiotics Don’t Work (And What to Do Instead) - Dr Colleen Cutcliffe

Update: 2025-07-28
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Episode: Are Your Probiotics Actually Doing Anything?

In this episode, I sit down with Dr. Colleen Cutcliffe, PhD biochemist and CEO of Pendulum, to break down the real science of the microbiome — and why most probiotic supplements fall short.

We cover:

  • What the microbiome actually is
  • The difference between probiotics, prebiotics, and postbiotics
  • Why most probiotics never reach your gut
  • The importance of Akkermansia muciniphila and Clostridium butyricum
  • What causes leaky gut and how to fix it
  • How fiber and polyphenols fuel your microbiome
  • Why your gut impacts blood sugar, cravings, and energy

This isn’t surface-level advice. It’s a deep dive into what the science really says — and what most supplement companies won’t tell you. If you’ve ever struggled with digestion, energy crashes, or food sensitivities, this episode is a must-watch.

Guest: Dr. Colleen Cutcliffe — Co-Founder and CEO of Pendulum

Host: Michael Tchao (@michaeltchao)

Subscribe for more science-backed conversations at the intersection of food, health, and function.


🎁 Special Offer: For 20% off Pendulum membership first orders, use code MICHAEL20

👉 Visit PendulumLife.com

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Why Most Probiotics Don’t Work (And What to Do Instead) - Dr Colleen Cutcliffe

Why Most Probiotics Don’t Work (And What to Do Instead) - Dr Colleen Cutcliffe

Functional Flavor