Why Most Probiotics Don’t Work (And What to Do Instead) - Dr Colleen Cutcliffe
Update: 2025-07-28
Description
Episode: Are Your Probiotics Actually Doing Anything?
In this episode, I sit down with Dr. Colleen Cutcliffe, PhD biochemist and CEO of Pendulum, to break down the real science of the microbiome — and why most probiotic supplements fall short.
We cover:
- What the microbiome actually is
- The difference between probiotics, prebiotics, and postbiotics
- Why most probiotics never reach your gut
- The importance of Akkermansia muciniphila and Clostridium butyricum
- What causes leaky gut and how to fix it
- How fiber and polyphenols fuel your microbiome
- Why your gut impacts blood sugar, cravings, and energy
This isn’t surface-level advice. It’s a deep dive into what the science really says — and what most supplement companies won’t tell you. If you’ve ever struggled with digestion, energy crashes, or food sensitivities, this episode is a must-watch.
Guest: Dr. Colleen Cutcliffe — Co-Founder and CEO of Pendulum
Host: Michael Tchao (@michaeltchao)
Subscribe for more science-backed conversations at the intersection of food, health, and function.
🎁 Special Offer: For 20% off Pendulum membership first orders, use code MICHAEL20
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