What are the oral hygiene tips that could save your life?  

Dave Asprey sits down with one of the most popular guests on the show, Naveen Jain, founder and CEO of Viome Life Sciences, to explore how your oral microbiome influences not just your dental health but your entire body. Naveen reveals groundbreaking insights into how imbalances in oral bacteria can trigger chronic inflammation, heart disease, and even cancer—and how understanding your unique microbiome can help prevent these risks. 

Discover why oral health goes far beyond brushing and flossing, how to optimize your oral microbiome for longevity, and why common mouthwashes may be doing more harm than good. Naveen also introduces cutting-edge solutions from Viome, including personalized oral lozenges and postbiotics, to elevate both your oral and overall health. 

In this episode, you’ll also uncover the exact foods to eat and avoid to live a longer, healthier, and more vibrant life. 

What you’ll learn in this episode: 

• The surprising link between your oral microbiome and chronic disease 

• Why bacterial diversity in your mouth is essential for overall health 

• How leaky gums drive systemic inflammation and increase health risks 

• The dangers of over-sterilizing your mouth and eliminating beneficial bacteria 

• Personalized solutions to improve oral and gut health with Viome 

• Actionable tips to optimize your oral microbiome for better longevity 

Resources:  

• 2025 Biohacking Conference – https://biohackingconference.com/2025 

• Viome Full Body Intelligence Test (Save $110) – https://www.viome.com/dave 

• Viome Instagram – https://www.instagram.com/viome 

• Learn More About Viome – https://viome.com 

• Danger Coffee – https://dangercoffee.com 

• Danger Coffee Instagram – https://www.instagram.com/dangercoffeeofficial/ 

• Dave Asprey’s Website – https://daveasprey.com 

• Dave Asprey’s Book: Smarter Not Harder – https://daveasprey.com/books 

• Dave Asprey’s Linktree – https://linktr.ee/daveasprey 

• Upgrade Collective: Join The Human Upgrade Podcast Live – https://www.ourupgradecollective.com 

• Own an Upgrade Labs – https://ownanupgradelabs.com 

• Upgrade Labs – https://upgradelabs.com 

• 40 Years of Zen – Neurofeedback training for advanced cognitive enhancement – https://40yearsofzen.com 

Sponsors: 

-Leela Quantum | Head to https://leelaq.com/DAVE for 10% off. 

-ARMRA | Go to https://tryarmra.com/ and use the code DAVE to get 15% off your first order. 

Timestamps: 

• 00:00 Introduction to Viome and Its Impact on Health 

• 00:53 Meet Naveen Jain: Visionary Behind Viome 

• 02:41 Understanding the Microbiome and Its Role in Health 

• 05:54 The Power of RNA Analysis in Personalized Health 

• 12:19 Diet, Microbiome, and Personalized Nutrition 

• 29:50 The Importance of Oral and Gut Health 

• 39:20 Debating the Benefits of Intermittent Fasting 

• 40:08 The Role of Gut Bacteria in Fasting and Diet 

• 42:12 Understanding Chronic Inflammation and Diet 

• 44:13 The Keto Diet Myths and Realities 

• 45:44 Oxalates and Superfoods What You Need to Know 

• 49:25 The Concept of Holobiont and Human Health 

• 56:21 The Five Pillars of Longevity 

• 01:02:04 The Importance of Quality Sleep 

• 01:05:18 Purpose and Community for a Longer Life 

• 01:09:48 Upcoming Topics and Final Thoughts 

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