mRNA Vaccine Research and Therapeutic Applications
Update: 2025-08-23
Description
Sources trace mRNA tech from basics to bedside: nucleoside-modified mRNA tames innate sensing and boosts translation; engineering across cap/UTRs/poly(A) plus purification optimizes stability and reduces immune noise. Lipid nanoparticles—especially ionizable lipids—are the enabling delivery system. Beyond infectious-disease vaccines, the field is moving toward on-demand/mobile manufacturing and immune-tolerance applications for autoimmunity/allergy, not just immune activation.
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