歡迎嚟到 搞乜咁科學 GMG Science 第11集！

今集嘅主題係2022新發現 New in 22’🗓！Keith會講數學家點樣將個圓形變成正方形，Abellona會解釋有咩方法製造到萬能嘅流感疫苗?

喂！好奇心，係時候醒喇 :)

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科學一齊搞 Got Something for GMG - 有咩想同我哋講都可以係度share㗎

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Show Notes and Links:

大部份今集有關嘅圖片會係我哋IG見到㗎

Keith’s part

學寫電腦程式竟然同學語言能力有關﹐反而同數感無乜關係? - Prat, C. S., et al. (2020). Relating natural language aptitude to individual differences in learning programming languages. Scientific reports, 10(1), 1-10.

較剪全等 Scissor Congruence - nLab 

三大尺規作圖問題 Impossible Constructions - Wikipedia

正方形原來係剪唔到變圓形㗎…

Dubins, L., Hirsch, MW, & Karush, J. (1963). Scissor congruence. Israel Journal of Mathematics, 1(4), 239-247.

可等分解 Equidecomposable - Wolfram MathWorld

…但分解佢就得喇!

Laczkovich, M. (1990). Equidecomposability and discrepancy; a solution of Tarski's circle-squaring problem. , 1990(404), 77-117.

宇宙有幾多原子？好多囉 - US Department of Energy’s Jefferson Lab

🟥 ➡️ 🔴 嘅進展

Grabowski, L., Máthé, A., & Pikhurko, O. (2016). Measurable equidecompositions for group actions with an expansion property, accepted by J. Eur. Math. Soc., E-print arxiv, 1601.

Marks, A. S., & Unger, S. T. (2017). Borel circle squaring. Annals of Mathematics, 186(2), 581-605.

終於變到喇!

Máthé, A., Noel, J. A., & Pikhurko, O. (2022). Circle Squaring with Pieces of Small Boundary and Low Borel Complexity. arXiv preprint arXiv:2202.01412.

正方形點變做圓形，去片!

Abellona’s part

過去一百年的流感大流行歷史 – CDC

流感病毒的結構

現時的流感疫苗是怎樣製造的

流感病毒撠手的地方: Antigen shift 抗原轉變 & Antigen drift 抗原飄移

研發萬能流感疫苗的策略

策略一: 同時針對多種HA亞種的mRNA疫苗

Arevalo, C.P., et al, 2022. A multivalent nucleoside-modified mRNA vaccine against all known influenza virus subtypes. Science, 378(6622), pp.899-904.

策略二: 誘使免疫系統針對HA的莖部的疫苗

Nachbagauer, R., et al., 2021. A chimeric hemagglutinin-based universal influenza virus vaccine approach induces broad and long-lasting immunity in a randomized, placebo-controlled phase I trial. Nature medicine, 27(1), pp.106-114.

策略三: 針對流感病毒表面的其他蛋白

Kim, K.H., et al., 2022. Universal protection against influenza viruses by multi-subtype neuraminidase and M2 ectodomain virus-like particle. PLoS pathogens, 18(8), p.e1010755.