From the Spectrum: Finding Superpowers with Autism

My guest today is Dr. Robert Melillo. Dr. Melillo shares his 35-year journey from athletic injuries and chiropractic roots to developmental cognitive neuroscience and founder of the Melillo Method. Driven by his own children’s challenges and a deep commitment to preserving their extraordinary gifts, he explains Autism as a treatable developmental imbalance rooted in brain immaturity—caused by retained primitive reflexes, disrupted right-left asymmetry, and poor transition from short-range to long-range connectivity. Emphasizing a bottom-up, root-cause approach over symptom management, he describes how remediating reflexes, stimulating right-brain activity, and balancing networks can unlock speech, motor control, and potential in non-speaking individuals—highlighting the human brain’s unique evolutionary vulnerability and adaptability while offering hope for meaningful change without erasing unique brilliance.Dr. Melillo https://www.drrobertmelillo.comYT https://www.youtube.com/@themelillomethodInstagram https://www.instagram.com/drrobertmelillo/White Board Series: Serotonin's Role in Development for Sensory Maps (not mood) https://youtu.be/Pbovstb82i4White Board Series: Basal Ganglia (Go/No-GO), Neural Correlates, & "Motivation" https://www.youtube.com/watch?v=hTW8CSPVEGcWhite Board Series: Basal Ganglia No-Go area & Arkeypallidial Cells https://www.youtube.com/watch?v=XHZ_5HthUWsDaylight Computer Company, use "autism" for $50 off at https://buy.daylightcomputer.com/autismChroma Light Devices, use "autism" for 10% discount at https://getchroma.co/?ref=autismFig Tree Christian Golf Apparel & Accessories, use "autism" for 10% discount at https://figtreegolf.com/?ref=autism0:00 Dr. Robert Melillo5:24 The Nature of Gifts & Vulnerabilities with Autism15:26 The Evolution of the Human Brain & Bipedalism; CNS is to move the living organism; Left Brain, Right Brain25:20 Functional Connectivity & Movements; Left Brain-Right Brain36:46 The Immature Brain; Autism means "Self"38:54 Interventions for Maturing the Brain & Movements42:46 The Melillo Method & Upstream Individualized Interventions47:47 GI and the Nervous Systems; Excitation/Inhibition52:21 Melillo Method55:40 Giving a Voice to Non-Verbals; Sensory Map, Somatosensory & Homunculus1:03:00 The Basal Ganglia & Motor Movements1:06:34 Bridging Clinical & Neuroscience Research & MethodsX: https://x.com/rps47586YT: https://www.youtube.com/channel/UCGxEzLKXkjppo3nqmpXpzuAemail: info.fromthespectrum@gmail.com

Video Link: https://www.youtube.com/watch?v=FA1QdeuGhJEIn this whiteboard-style episode, we dive deep into the auditory brainstem response (ABR) and its profound implications for the autistic phenotype, tracing sound from the cochlea's powerful endocochlear potential through multi-step brainstem relays to the thalamus and auditory cortex. Highlighting high excitation paired with low inhibition, we map how poor filtering at key stations—like the superior olivary complex, lemniscus, and inferior colliculus—leads to listening dissonance, where sounds blend uncontrollably into overwhelming noise. The discussion underscores the mesencephalon's critical role in sensory gating, binaural processing, and the tragic risks of overload, emphasizing why compromised inhibition cascades into sensory chaos and the urgent need for understanding these upstream mechanisms.Daylight Computer Company, use "autism" for $50 off at https://buy.daylightcomputer.com/autismChroma Light Devices, use "autism" for 10% discount at https://getchroma.co/?ref=autismFig Tree Christian Golf Apparel & Accessories, use "autism" for 10% discount at https://figtreegolf.com/?ref=autismCognity AI for Autistic Social Skills, use "autism" for 10% discount at https://thecognity.com00:00 auditory processing episode: low inhibition + high excitation = sensory overload; mesencephalon key for hearing, vision, motor in autism00:55 ABR & Mesencephalon Focus Review prior ABR episode (wave 5 emphasis); mesencephalon central for toxicity phenotype sensory issues01:17 Brainstem Anatomy Slices Sliced brainstem views: medulla, pons (football shape), small mesencephalon, thalamus/subcortical above02:17 Hearing vs. Vision Pathways Hearing multi-step (cochlea → brainstem → thalamus); vision faster (retina → lateral geniculate/superior colliculus)03:21 Cochlea & Endocochlear Potential Spiral cochlea powers hearing; highest DC voltage (endocochlear potential ~+85-100mV) via potassium gradient; melanin underrated07:56 ABR Waves 2-7 Breakdown Wave 2: exiting cochlea; 3: cochlear nuclei sync; 3-4: superior olivary/lemniscus (ITD/ILD binaural, glycine/GABA inhibition); 5: inferior colliculus; 6-7: medial geniculate to A1 cortex14:17 Inferior Colliculus Role Glutamatergic excitation; binaural convergence; gamma needed for suppression (challenging in autism)17:01 Thalamus Entry & TRN Gating Wave 6: subcortical/thalamus; TRN (GABA sectors) filters sensory; compromised in autism risks overload23:20 Listening Dissonance Intro Sounds blending issue in autism; starts at olivary/lemniscus due to poor inhibition; firehose-like overload35:59 Signal-to-Noise & Prefrontal Effort High excitation/low inhibition = noise dominance; recruits medial prefrontal/ACC/insula for top-down control40:50 Overwhelm Consequences Hijacked emotional circuits (amygdala, insula); leads to shutdown/elopement; avoid talking when overwhelmed.X: https://x.com/rps47586YT: https://www.youtube.com/channel/UCGxEzLKXkjppo3nqmpXpzuAemail: info.fromthespectrum@gmail.com

Link to video: https://www.youtube.com/watch?v=_NL6RCFsiVgIn this detailed whiteboard-style episode, we explore the superior colliculus within the mesencephalon (midbrain) and its critical role in the autistic phenotype. Focusing on rapid visual processing, we explain how ~15% of retinal fibers bypass the thalamus to directly reach the superior colliculus for fast gaze orientation and saccades, while heightened gamma waves and imbalanced feedforward/feedback loops contribute to sensory overload, delayed eye movements, and challenges in attention modulation. Connections to the thalamus, frontal eye fields, basal ganglia, and cranial nerves are mapped out, underscoring the midbrain's evolutionary primacy in sensory integration, motor control, and external orientation—highlighting why disruptions here profoundly impact autistic neurology.Daylight Computer Company, use "autism" for $50 off at https://buy.daylightcomputer.com/autismChroma Light Devices, use "autism" for 10% discount at https://getchroma.co/?ref=autismFig Tree Christian Golf Apparel & Accessories, use "autism" for 10% discount at https://figtreegolf.com/?ref=autismCognity AI for Autistic Social Skills, use "autism" for 10% discount at https://thecognity.com00:00 Mesencephalon in Autism Midbrain issues in autism: eye movements (superior colliculus), hearing (inferior colliculus), motor (basal ganglia links)01:04 Brainstem Diagram Diagram: inferior colliculus (auditory, green); superior colliculus (visual relay, red); thalamus with geniculate bodies02:09 Retinal Projections Melanin-rich retina → ~15% direct fibers to superior colliculus for fast gaze/orientation; rest to lateral geniculate03:41 Superior Colliculus Outputs Descending to cranial nerves 3/4/6 (eyes), 9-12 (head), vagus (10); rapid visual-motor responses05:33 Thalamus Protection Thalamus sensory hub; protected by inhibitory TRN shell (parvalbumin/somatostatin, GABA-A/B)08:11 Sensory Filtering Risk TRN filters overload; poor filtering in autism risks schizophrenia-like sensory flood10:03 Fast Pathway to Frontal Eye Fields Retina → superior colliculus → pulvinar → mediodorsal thalamus → frontal eye fields; gamma-driven speed in autism12:24 Cortical Links Superior colliculus connects to V1-V5, somatosensory, sensory-motor cortex; delayed feedback in autism15:05 Basal Ganglia Role Superior colliculus → substantia nigra reticulata & globus pallidus interna; fast outputs, delayed feedback affects saccades17:37 Mesencephalon Core Functions Sensory integration (via thalamus/cerebellum); motor control (basal ganglia); external attention orientation20:08 Brain Waves in Autism Autism: high gamma dominance vs. typical alpha/beta; theta-gamma coupling for task switching often overwhelmed21:14 Midbrain Evolutionary Note Mesencephalon (functional core) not anatomically middle; later cortex can interfere with its precise roles.X: https://x.com/rps47586YT: https://www.youtube.com/channel/UCGxEzLKXkjppo3nqmpXpzuAemail: info.fromthespectrum@gmail.com

This is an audio version of a white broad series covering inhibition/thalamic reticular nucleus. See the video to follow along. Here: https://youtu.be/XLoKW8Wc0Kc?si=xRDdSaFskKB3e5ZbThis episode provides a detailed exploration of the thalamic reticular nucleus (TRN), the inhibitory "shell" surrounding the thalamus that acts as a sensory gate in the brain. Drawing on prior episodes, it explains how abnormalities in TRN development—linked to factors like Sonic Hedgehog signaling knockouts, reduced parvalbumin interneurons, and genes such as CNTNAP2—contribute to the excitation-inhibition imbalance central to autism. The TRN regulates sensory input access (visual, auditory, somatosensory), attention modulation, sleep-wake cycles, and overload protection; in autism, its dysfunction leads to sensory overload, hyperactivity, repetitive behaviors, and social challenges, while offering strengths like accelerated learning, intense focus, and enhanced visual thinking due to heightened inner-directed processing.83: Thalamic Reticular Nucleus (TRN), Sensory Gating & Autism https://youtu.be/cjwbog7Rk4c?si=R3Nq3Hs5A0M_7Vts82: Sonic Hedgehog & Inhibitory Neurons in Autism https://youtu.be/Oee4L7Vsj4E?si=rG2T8R9AIYAnDBw776: Parvalbumin Interneurons & the Autistic Phenotype https://youtu.be/PBHVssvoQkM?si=saFvjVx9Bjq610pkAlso see the Visual Thinking episodesDaylight Computer Company, use "autism" for $50 off at https://buy.daylightcomputer.com/autismChroma Light Devices, use "autism" for 10% discount at https://getchroma.co/?ref=autismFig Tree Christian Golf Apparel & Accessories, use "autism" for 10% discount at https://figtreegolf.com/?ref=autismCognity AI for Autistic Social Skills, use "autism" for 10% discount at https://thecognity.com00:00 Introduction, Episode Recap, TRN Overview02:45 TRN Anatomy Drawing, Thalamus Structure and Shell05:18 Sonic Hedgehog Role, Knockout Models in Development10:48 Cell Types in TRN, Parvalbumin vs Somatostatin Functions15:19 TRN Sectors, Sensory Inputs (Visual/Auditory/Somatosensory) Access20:37 Cortical Connections, Layer 6 Feedback and Crosstalk25:04 Mini-Columns Recap, Thalamus to Layer 4 Processing29:56 Prefrontal Cortex Mapping, Adaptive Responses Role34:22 TRN Functions: Attention Modulation, Sleep-Wake Regulation36:22 CNTNAP2 Discussion, Knockout Phenotypes (Hyperactivity, Seizures)38:45 Strengths/Weaknesses: Accelerated Learning, Visual Thinking Benefits42:18 Overload Protection, Hyperactivity, Social/Repetitive Challenges46:30 Conclusion, Autism as "Self," Inner-Directed ProcessingX: https://x.com/rps47586YT: https://www.youtube.com/channel/UCGxEzLKXkjppo3nqmpXpzuAemail: info.fromthespectrum@gmail.com

My guest today is Len Arcuri. Len is a devoted father turned passionate advocate who shares his transformative journey with raw honesty and profound insight. From the shock of his son's moderate-to-severe autism diagnosis and severe health challenges to witnessing remarkable progress through personal growth, root-cause exploration, and unconventional approaches like homeopathy, Len illustrates how a parent's internal shift can unlock a child's potential. With unwavering compassion, he empowers families to lighten self-imposed burdens, embrace informed intuition, reject limiting labels, and prioritize their own empowerment as the greatest intervention—turning a once-overwhelming path into one of deeper connection, resilience, and hope.Autism Parenting Secret Website (Amazing !) https://autismparentingsecrets.comEpisodes https://autismparentingsecrets.com/podcast/Elevate How You Navigate https://elevatehowyounavigate.comemail: hello@allinparent.com0:00 The essence of Autism Parenting Secrets podcast & Len's work01:49 Chroma Light Devices, use "autism" for 10% discount02:43 Daylight Computer Company, use "autism" for $50 discount04:24 Fig Tree Golf, use "autism" for 10% discount04:58 Cognity AI, use "autism" for 10% discount05:56 Len Arcuri & his family's journey into Autism06:28 Regression & Diagnosis Regression noticed around 13 months; diagnosed moderate-to-severe Autism at 18 months07:15 Son's Dramatic Progress From thought nonverbal forever to highly verbal and joyful; credits massive parenting shift and acceptance09:39 Self-Generated Weight & Mindset Most emotional heaviness self-created (worry/frustration); growth mindset key; embrace mistakes13:41 Pivotal Shift Moment "No one is coming"; parent must lead decisions; reject victim mentality and negative self-talk14:14 Early Influences & Intuition "Do what it takes" attitude; rejected conventional playbook; prioritized maternal intuition21:50 Speech Tied to Physical Health & delay linked to severe GI issues and life-threatening allergies; homeopathy sparked rapid turnaround27:45 Navigating the school years36:20 Podcast Origin & Purpose41:10 EMF as Stressors & simple fixes help46:38 EMF Science & oxidative stress; children more vulnerable58:03 Root Causes Overview Candidates: EMFs, chemicals, glyphosate, vaccines, Tylenol; focus on child's unique factors01:07:21 Role with Dr. Bogner01:11:14 Transition to Coaching & helping parents transform into confident decision-makers01:26:35 View on Autism Label01:33:54 Contact & 2026 Vision Coaching: elevatehowyounavigate.com; Podcast: autismparentingsecrets.com; 2026 = year of empowered parents avoiding unnecessary sufferingX: https://x.com/rps47586YT: https://www.youtube.com/channel/UCGxEzLKXkjppo3nqmpXpzuAemail: info.fromthespectrum@gmail.com

This episode examines auditory processing challenges in autism, focusing on "listening dissonance"—the overwhelming blending of sounds due to reduced inhibition in the auditory brainstem pathway. It explains how high excitation and low parvalbumin interneuron activity cause unfiltered sensory input from the cochlear nucleus through the superior olive and inferior colliculus to overwhelm the thalamus and auditory cortex. Using a water hose analogy, the episode illustrates how poor filtering leads to sensory overload, recruiting higher cortical areas like the medial prefrontal cortex and salience network (ACC and anterior insula) in a failed top-down attempt to quiet noise. The result is emotional hijacking, adaptive failure, and real-world risks like fleeing to dangerous places, with practical implications like noise-canceling headphones and the need for understanding in autism support.Daylight Computer Company, use "autism" for $50 off at https://buy.daylightcomputer.com/autismChroma Light Devices, use "autism" for 10% discount at https://getchroma.co/?ref=autismFig Tree Christian Golf Apparel & Accessories, use "autism" for 10% discount at https://figtreegolf.com/?ref=autismCognity AI for Autistic Social Skills, use "autism" for 10% discount at https://thecognity.com00:00 Listening Dissonance Introduction, Auditory Filtering02:15 Excitation-Inhibition Imbalance, Seesaw Analogy 04:30 Brainstem Auditory Pathway, Superior Olive, Inferior Colliculus07:45 Water Hose Analogy for Sensory Overload, Inhibition as Filter10:50 Auditory Cortex Role, Thalamus Recruitment, Mini-Columns13:20 Prefrontal Cortex Top-Down Control, Medial/Orbital Areas16:10 Salience Network Hijacking, ACC and Anterior Insula19:00 Emotional Circuits Overload, Adaptive Response Failure21:40 Real-World Implications, Drowning Risks, Noise-Canceling Headphones24:30 Conclusion, Beatles Music Blend Comparison, Future Episode TeaseX: https://x.com/rps47586YT: https://www.youtube.com/channel/UCGxEzLKXkjppo3nqmpXpzuAemail: info.fromthespectrum@gmail.com

Audio version of a White Board Series to help explain the content of the podcast.Here: https://youtu.be/wCWOM5Dyp2kShorts:https://youtu.be/G5I63MIC8OEhttps://youtu.be/9ZRk8aTGVVohttps://youtu.be/rcmSDgsylV8https://youtu.be/rcmSDgsylV8Episodes:https://youtu.be/gZdg9bX3Nuw?si=-WaqGnkF_xDXXbg8 https://youtu.be/ZPkb1Fp7EIc?si=5vP5z5ZnkycJcFFNhttps://youtu.be/wzqRFmHCdlM?si=No8JAquAkqTXlOyqhttps://youtu.be/1E53ZYehUCU?si=tGE4YQHmi08sOmfkhttps://youtu.be/NOVp4mIroug?si=Ys6ZJF9Gvnv83_tSDaylight Computer Company, use "autism" for $50 off at https://buy.daylightcomputer.com/autismChroma Light Devices, use "autism" for 10% discount at https://getchroma.co/?ref=autismFig Tree Christian Golf Apparel & Accessories, use "autism" for 10% discount at https://figtreegolf.com/?ref=autismCognity AI for Autistic Social Skills, use "autism" for 10% discount at https://thecognity.com00:00 Autistic Phenotype Core: Central, Peripheral, Enteric Nervous Systems03:40 Neurulation Introduction, Embryogenesis Recap, Neuroplate Formation07:20 Sonic Hedgehog Role, Proliferation, Motor/Interneurons, Thalamic Reticular Nucleus11:00 PTEN Pathway, mTOR, PIP Lipids, Cell Growth/Differentiation14:40 MTHFR (B9/Folate), Leukovorin, Methionine/Tryptophan Links18:20 Tryptophan as Aromatic Amino Acid, Maternal Serotonin, Neurite Overgrowth22:00 Brain Subdivision: Prosencephalon, Mesencephalon, Rhombencephalon Development26:00 Mesencephalon Anatomy: Substantia Nigra, Red Nucleus, Superior & Inferior Colliculi, Cranial Nerves30:00 Mesencephalon Functions: Motor Control, Sensory Integration, Attention Orienting, Autistic Phenotype TiesX: https://x.com/rps47586YT: https://www.youtube.com/channel/UCGxEzLKXkjppo3nqmpXpzuAemail: info.fromthespectrum@gmail.com

This is the audio version of a White Board Series.Video https://youtu.be/ocE0__RrTjM?si=oYsu4v4vyunt9RMDInsula and Salience Network https://youtu.be/XpzXkN-5ghA?si=0_3RKXe3C9aRZgERAutism & Salience Network on 6 weeks old https://youtu.be/_JQdir0V6Cg?si=pwJUzwv4BaspWluXFull Episode Spindle Neurons, Salience Network, & Social Behaviors https://youtu.be/FlPMVHnls-4?si=NyGyzrAknwVwNSGSFull Episode Autism and Adaptive Responses, and exploring the mPFC, ACC, and Insula https://youtu.be/Zj3_e6ZjCGk?si=VhHRN9HG5tJGKfcEFull Episode Autism and the Salience Network https://youtu.be/9ZbTztb3al8?si=WVv1txx39Y42l09bVon Economo neurons (VEN), sometimes called Spindle Neurons, are the brain’s rare, giant ‘social superhighway’ cells that let us make split-second intuitive judgments in complex social environments — and in autism these cells are significantly abnormal- some increased amounts in key brain hubs, some morphological impairments like altered soma, dendrite, or cytoarchitecture (remember microtubules for this role, too). These abnormal developed VENs are pulling the salience network toward raw sensory input instead of flexible social cognition.Daylight Computer Company, use "autism" for $50 off at https://buy.daylightcomputer.com/autismChroma Light Devices, use "autism" for 10% discount at https://getchroma.co/?ref=autismFig Tree Christian Golf Apparel & Accessories, use "autism" for 10% discount at https://figtreegolf.com/?ref=autismCognity AI for Autistic Social Skills, use "autism" for 10% discount at https://thecognity.com00:00 Spindle Neurons Introduction, Discovery, Species03:40 Brain Regions, Rapid Transmission, Neuropeptide Y07:20 Anterior Cingulate Cortex (ACC) Roles, Adaptive Responses11:00 Insula Functions, Salience Network Hubs14:40 Salience Network Nodes, Infant fMRI Study (UCLA 2024)18:20 Spindle vs Pyramidal Neuron Shape, Layer 5B Location22:00 Spindle Neurons in Autism, Lack of Adaptive ResponsesX: https://x.com/rps47586YT: https://www.youtube.com/channel/UCGxEzLKXkjppo3nqmpXpzuAemail: info.fromthespectrum@gmail.com

This is the audio for a video/white board instruction on Autism & Minicolumns.Here: https://youtu.be/G-DCzqle98A?si=432B8QQBSarS9Grzhttps://youtu.be/X8VYHygHEDY?si=UH4o6jI4XqPGxT3Hhttps://youtu.be/sL4SZuD4lOQ?si=6ylDUZqyv868FuemDaylight Computer Company, use "autism" for $50 off at https://buy.daylightcomputer.com/autismChroma Light Devices, use "autism" for 10% discount at https://getchroma.co/?ref=autismFig Tree Christian Golf Apparel & Accessories, use "autism" for 10% discount at https://figtreegolf.com/?ref=autismCognity AI for Autistic Social Skills, use "autism" for 10% discount at https://thecognity.com00:00 Sensory Processing, Autistic Learning, Many Columns03:45 Excitation Inhibition Balance, Recent Episodes Review07:20 Brain Waves, Gamma Processing, Default Go System11:10 Visual Sensory Pathway, Brain Regions, Eye Movements15:50 Myelination Issues, Fasciculi, Mini Columns Structure19:30 Column Density, Autism Phenotype, Lack of Pruning23:40 Signal Flow in Layers, Intelligence, Firing Patterns27:15 Thalamus Role, Dissociation Note, Learning BenefitsX: https://x.com/rps47586YT: https://www.youtube.com/channel/UCGxEzLKXkjppo3nqmpXpzuAemail: info.fromthespectrum@gmail.com

Starting with von Békésy’s traveling wave and the cochlea’s +80 mV biological battery, we move millisecond-by-millisecond through the auditory brainstem response (ABR Waves I–V), auditory nerve, cochlear nucleus, superior olivary complex, inferior colliculus, thalamic reticular nucleus, and finally primary auditory cortex (A1). The Endocochlear Potential (EP) is the highest DC voltage in the human body. As signals travel, excitation-inhibition attempts to balance that. When intact, brains can filter noise and locate meaningful sound. In Autism, reduced GABAergic sculpting (parvalbumin, somatostatin, and VIP interneuron dysfunction) plus lower myelination and a delayed Wave V — already detectable on the newborn hearing screen — turn ordinary environments into an unfiltered flood. The result is listening dissonance: a moment-to-moment perceptual struggle that collapses 40-Hz gamma, recruits massive frontal effort and emotional regions of the brain, frequently ends in sensory overload, shutdown, or literal pain. We close with the exact equation the pathway reveals: Low Inhibition + High Excitation = Sensory Overload.Daylight Computer Company, use "autism" for $50 off at https://buy.daylightcomputer.com/autismChroma Light Devices, use "autism" for 10% discount at https://getchroma.co/?ref=autismFig Tree Christian Golf Apparel & Accessories, use "autism" for 10% discount at https://figtreegolf.com/?ref=autismCognity AI for Autistic Social Skills, use "autism" for 10% discount at https://thecognity.com0:00 Chroma Light Devices and Daylight Computer Company01:56 Audition & Autism; von Békésy Traveling Wave & Tonotopy; Hair Cells & Cochlear Amplifier04:20 Endocochlear Potential (+80 mV Battery); Bioelectric Currents06:30 Stria Vascularis, Melanin, & Water Role08:15 Auditory Nerve – ABR Wave I (1.6 ms)08:36 ABR Wave II (2.7 ms)09:00 Cochlear Nucleus & Early E:I12:10 ABR Wave III – Superior Olivary Complex (3.8 ms)12:13 Binaural Processing & Calyx of Held15:00 ABR Wave V – Inferior Colliculus (5.6 ms)15:42 Inferior Colliculus Gamma & Cell Types18:00 Thalamus MGN & TRN Noise-Canceling21:30 2021 Newborn ABR Study – Prolonged Wave V Biomarker24:30 Listening Dissonance Explained28:30 Auditory Cortex Gamma Collapse in Autism32:30 Primary Auditory Cortex A1 Mini-Columns36:00 Parvalbumin, Somatostatin & VIP Interneurons39:00 Formula: Low GABA + High Excitation = Overload & PainX: https://x.com/rps47586YT: https://www.youtube.com/channel/UCGxEzLKXkjppo3nqmpXpzuAemail: info.fromthespectrum@gmail.com

Dr. Sabine Hazan is a pioneering gastroenterologist and the first physician to launch a private microbiome testing lab in the U.S. In this powerful episode, she reveals how decades of clinical experience and cutting-edge research have convinced her that the gut microbiome—especially the near-extinction of key bacteria like Bifidobacteria—lies at the root of Autism, Alzheimer’s, cancer, and many chronic diseases. Speaking candidly about the erosion of the doctor-patient relationship, relentless censorship, and the profit-driven forces that have turned medicine into a pill-pushing machine, Dr. Hazan explains why she believes the art of medicine is dying—and how restoring the microbiome could bring it back to lifeProgenabiome: https://progenabiome.comClinical Trials: https://progenabiome.com/clinical-trialsX: https://x.com/SabinehazanMDChroma Light Devices, use "BFCM2025" for 21% discount at https://getchroma.co/?ref=autismUse "autism"$50 discount https://buy.daylightcomputer.com/autism10% discount https://figtreegolf.com/?ref=autismhttps://thecognity.com0:00 Chroma, use "BFCM2025"; Daylight Computer & Fig Tree Golf, use "autism"2:00 Dr. Sabine Hazan; Gastroenterologist; Microbiome; Fecal Transplant; Covid, Alzheimers, Cancer, Gut Conditions7:12 The Impact of COVID on Medical Perspectives; Censorship & Narratives12:26 The Art of Medicine & Relationships- more than just pills (Big Harma)16:28 Understanding Autism & Microbiome connections; Cancer21:16 Challenges with Clinical Trials & Funding26:58 Innovations in Treatment versus the Status Quo31:44 Censorship & Narrative Control (Profits over Humanity); Dr. Andy Wakefield & Autism35:52 The Role of Vaccines & Antibiotics40:16 Future of Microbiome Research & Treatment; Bifidobacteria47:52 Preserving the Microbiome; Mother's & Autism; Autism Research54:18 Fighting Censorship in Science; Narrative Control1:00:56 Lab Testing for Autism; Red Light; Dr. Jack Kruse1:09:14 Collaborating versus Censorship1:13:03 Humanity & Health; Profits over Humanity1:17:27 The Medical Oath; Urgency in Microbiome & BifidobacteriaX: https://x.com/rps47586YT: https://www.youtube.com/channel/UCGxEzLKXkjppo3nqmpXpzuAemail: info.fromthespectrum@gmail.com

This episode dives deep into excitatory neurons—the brain’s primary “go” signal—and their outsized role in the Autistic phenotype. We explore how pyramidal neurons, powered by glutamate through AMPA and NMDA receptors, drive lightning-fast information transmission, synaptic hyperplasticity via BDNF, and elevated gamma oscillations (30–80 Hz) in V1, S1, and A1. This overactive excitatory push, paired with reduced parvalbumin and somatostatin inhibition, creates the well-documented E:I imbalance that fuels sensory hypersensitivity, one-trial learning, rigid memory encoding, repetitive behaviors, and the classic distal-connection timing mismatch from early sensory cortices to prefrontal regions.The Autistic brain gets to the first two stops blazingly fast yet struggles to reach the final destination typical brains arrive at effortlessly.Inhibition Episodes: https://youtu.be/cjwbog7Rk4c?si=uSaLLNmS5EJLa_iHhttps://youtu.be/Oee4L7Vsj4E?si=Y5F2eVudCLhkxNw1https://youtu.be/PBHVssvoQkM?si=A6SPedQi-Dt-DVO_E/I https://youtu.be/ETChjRQ0SzQ?si=yIFNovzldwSZRMeThttps://youtu.be/jl0xwjnyXII?si=dmk49CMQo3Uf17axDaylight Computer Company, use "autism" for $50 off at https://buy.daylightcomputer.com/autismChroma Light Devices, use "autism" for 10% discount at https://getchroma.co/?ref=autismFig Tree Christian Golf Apparel & Accessories, use "autism" for 10% discount at https://figtreegolf.com/?ref=autismCognity AI for Autistic Social Skills, use "autism" for 10% discount at https://thecognity.com00:00 Excitatory Neurons, Push-Pull System, Parvalbumin Deficiency03:30 E:I Imbalance, Sensory Hypersensitivity, Repetitive Behaviors07:00 Pyramidal Neurons, Glutamate, AMPA/NMDA Receptors10:30 Brain Regions: DLPFC, Anterior Insula, V1 S1 A114:00 Amygdala Misnomer, Low Road vs High Road, Emotional Hub18:30 Receptors: AMPA 1-5ms, NMDA 10-200ms, mGluR Modulatory22:00 Gamma Oscillations, BDNF Hyperplasticity, Sensory Overload25:30 Distal Connections, Point-A-to-Point-B Timing Mismatch29:00 BDNF Critical Period, One-Trial Learning, Rigid Memory32:30 TRN Dysfunction, Repetitive Behaviors, Corticostriatal Circuit34:30 Go-Signal vs Stop-Signal, Push-Pull Bowling Bumpers36:00 Rubenstein & Merzenich 2003, E:I Imbalance Foundation37:08 Daylight Computer Company, use "autism" for $50 discount39:32 Chroma Light Devices, use "autism" for 10% discount42:35 Reviews/Ratings & Contact InfoX: https://x.com/rps47586YT: https://www.youtube.com/channel/UCGxEzLKXkjppo3nqmpXpzuAemail: info.fromthespectrum@gmail.com

Today's episode examines the thalamic reticular nucleus (TRN), a GABAergic structure that filters sensory inputs to the thalamus, influencing sensory processing and attention in Autism. We'll explore how TRN dysfunction contributes to sensory hypersensitivity, repetitive behaviors, and cognitive strengths like visual thinking. We cover the TRN’s visual, somatosensory, auditory, and limbic sectors, using vivid analogies like a security guard and staring contest to illustrate its role. These mechanisms are linked to the Autistic phenotype’s challenges and unique perceptual abilities.Daylight Computer Company, use "autism" for $50 off athttps://buy.daylightcomputer.com/autismChroma Light Devices, use "autism" for 10% discount athttps://getchroma.co/?ref=autismuse "autism" for 10% discount at Fig Tree Christian Golf Apparel & Accessories https://figtreegolf.com/?ref=autismCognity AI for Autistic Social Skills, use "autism" for 10% discount athttps://thecognity.com00:00 Thalamic reticular nucleus (TRN), GABAergic neurons, sensory gating03:42 TRN functional roles, sensory gating, attentional modulation, brainwave generation, neuro-overload prevention07:44 TRN inputs, basal ganglia, repetitive behaviors11:15 Cognitive flexibility, prefrontal cortex, dorsal striatum, rigid responses, Autistic rigidity14:38 TRN outputs, feedback inhibition, excitatory neurons, sensory tuning, gamma oscillations18:35 Burst firing, tonic firing, sensory suppression, attention regulation, sleep spindles22:12 Visual sector, "staring contest" analogy, parvalbumin & VIP interneurons, lateral geniculate nucleus, visual gating25:50 Somatosensory sector, ventral basal complex, tactile hypersensitivity, sensory-emotional integration29:15 Auditory sector, medial geniculate nucleus, auditory sensitivity, social processing deficits, clusters of noises in the environment, Beatles song comparison33:00 Limbic sector, mediodorsal nucleus, anterior insula, emotional regulation, OCD-like behaviors, Leading the way in Adaptive Responses36:47 TRN security guard analogy, sensory control, thoughts and plans, high-intensity stimuli40:20 Visual attention, high gamma activity, subtle environmental cues, Autistic cognitive strengths41:06 Daylight Computer Company, use "autism" for $50 discount43:25 Chroma Light Devices, use "autism" for 10% discountX: https://x.com/rps47586YT: https://www.youtube.com/channel/UCGxEzLKXkjppo3nqmpXpzuAemail: info.fromthespectrum@gmail.com

Today's episode explores the role of inhibitory neurons & the Sonic Hedgehog (SHH) gene in shaping the Autistic phenotype, focusing on the excitation-inhibition imbalance that drives sensory hypersensitivity and cognitive challenges. Through a neuroscience lens, the episode connects these mechanisms to heightened gamma activity.Ben Ari Episode https://youtu.be/jo-ffwF9u0YParvalbumin Interneurons episode https://youtu.be/PBHVssvoQkM?si=t8WYGlcHcv7WiE-TVisual Thinking Part 1 https://youtu.be/XqQ8jCvWzYc?si=lffUEjGHjWj4mGOMNeurulation Part 1 https://youtu.be/gZdg9bX3Nuw?si=xvwtlz-p1hPHI8FADaylight Computer Company, use "autism" for $50 off athttps://buy.daylightcomputer.com/autismChroma Light Devices, use "autism" for 10% discount athttps://getchroma.co/?ref=autismuse "autism" for 10% discount at Fig Tree Christian Golf Apparel & Accessories https://figtreegolf.com/?ref=autismCognity AI for Autistic Social Skills, use "autism" for 10% discount athttps://thecognity.com00:00 - Autistic phenotype, excitation-inhibition imbalance, sensory hypersensitivity, cognitive deficits03:40 - Inhibitory neurons, GABA receptors, GABA-A, GABA-B, GABA-C, tonic inhibition07:24 - Tonic firing, burst firing, phasic firing, neural oscillations, sensory processing08:31 - Sonic Hedgehog gene, neural development, GABAergic identity, thalamic reticular nucleus (TRN)14:48 - Parvalbumin interneurons, fast-spiking, gamma oscillations, sensory gating, dorsolateral prefrontal cortex18:22 - Parvalbumin dysfunction, sensory hypersensitivity, visual cortex (V1), EI imbalance, brain-derived neurotrophic factor (BDNF)22:02 - Somatostatin interneurons, feedback inhibition, dendritic modulation, sensory adaptation, hippocampus25:43 - Vasoactive intestinal peptide (VIP) interneurons, disinhibition, pyramidal activity, attention, social processing29:30 - Calbindin interneurons, calretinin interneurons, dendritic inhibition, sensory processing, anterior insula33:15 - Purkinje cells, cerebellum, motor control, cognitive timing, cell loss in autism36:00 - Evolutionary perspective, parvalbium density, neural circuit stabilization, sensory-cognitive processing39:25 - Gamma activity, visual processing, retina, lateral geniculate nucleus, attention to detail, autistic self39:52 Daylight Computer Company, use "autism" for $50 discount42:13 Chroma Light Devices, use "autism" for 10% discount45:17 Reviews & Contact InfoX: https://x.com/rps47586YT: https://www.youtube.com/channel/UCGxEzLKXkjppo3nqmpXpzuAemail: info.fromthespectrum@gmail.com

In this episode, we explore the connections between Autism and Parkinson's, focusing particularly on the basal ganglia and its substructures, notably the substantia nigra within the midbrain. We discuss how the substantia nigra, known for its high concentration of neuromelanin, plays a critical role in these disorders. The episode examines how neuromelanin, a dark pigment, not only absorbs all frequencies of light but also has antioxidant properties, binds metals, and acts as a neuroprotector. This discussion leads into the broader implications of environmental signals, particularly light, on human biology, touching on how modern changes in light exposure might affect these conditions.We examine the role of tyrosine in the synthesis of neuromelanin and its derivatives like dopamine, which are crucial for neural function. We look at how deficiencies or imbalances in these pathways could lead to the symptoms observed in Autism and Parkinson's, including motor function issues. The conversation also covers the direct and indirect pathways in the basal ganglia, explaining how these pathways facilitate or inhibit movement, respectively, and how their dysfunction can manifest in the characteristic motor symptoms of both disorders. We also touch on the significance of thyroid function, particularly the roles of T3 and T4 hormones, in brain development and neuron health, tying these elements back to the overarching theme of energy loss and transduction in both Autism and Parkinson's.Autism and Parkinson's are a lack of, or a loss of, energy.Biological Energy: Quantum Mechanisms, Water, DHA, and NF-kB: https://youtu.be/2-IA_gunXbwDaylight Computer Company, use "autism" for $50 off athttps://buy.daylightcomputer.com/autismChroma Light Devices, use "autism" for 10% discount athttps://getchroma.co/?ref=autismCognity AI for Autistic Social Skills, use "autism" for 10% discount athttps://thecognity.com0:00 Autism and Parkinson's; Basal Ganglia; Substantia Nigra; Neuromelanin; Internal Calculators2:15 Tyrosine; Chromophores; Aromatic Amino Acids3:50 Biological Energy; Mitochondria; Environmental Signals; Cytochrome C Oxidase; Autism Research Miss6:20 Deep Brain Stimulation6:48 Neuromelanin9:02 Reverse Engineer ATPase10:48 Tree Examples11:45 Hypoxia and loss of energy & dopamine12:26 Eyes, hair, & skin; RPE; efficiency & power; What is Light?13:58 Light; Information & Energy; electromagnetic; wave-particle duality; sunlight versus artificial light17:08 Thyroid; T3 & T4; Iodine18:31 Roles of T323:00 Loss of energy in the womb & Autism research25:00 Melanin + Water = Electrons26:40 Basal Ganglia; "Motivations" & Movements; Direct Pathway30:55 Indirect Pathway32:52 Go, No-Go; Action selection, learning & habits; fine motor skills34:18 Parkinson's and loss of timing & energy; modulating the two pathways & dopamine37:07 Reviews/Ratings & contact infoX: https://x.com/rps47586YT: https://www.youtube.com/channel/UCGxEzLKXkjppo3nqmpXpzuAemail: info.fromthespectrum@gmail.com

In this episode, Dr. Ahmad Ammous, MD, exposes the profit-driven "profit mills" of modern medicine, critiquing its reliance on pills to manage symptoms rather than address root causes. Drawing from his journey as an internal medicine physician, he challenges pharmaceutical-centric practices and delves into quantum biology’s healing potential, exploring topics like light-driven energy production through melanin’s water-splitting mechanism, cytochrome sensitivity to red and blue light in the electron transport chain, and circadian biology’s role in melatonin and cortisol regulation. Dr. Ammous offers practical solutions, such as paleo diets and sunlight exposure, to optimize health, while advocating for decentralized systems, including Bitcoin, to empower patients over profits.Modern Medicine is Profits over HumanityTHIS IS NOT MEDICAL ADVICECentralized Medicine = PROFITS over HUMANITYDr. Ammous X https://x.com/AmmousMDDr. Ammous website https://ammousmd.com/?v=eb65bcceaa5fDaylight Computer Company, use "autism" for $50 off athttps://buy.daylightcomputer.com/autismChroma Light Devices, use "autism" for 10% discount athttps://getchroma.co/?ref=autismCognity AI for Autistic Social Skills, use "autism" for 10% discount athttps://thecognity.com0:00 Dr. Ahmad Ammous, MD; Internal Medicine Medical Doctor5:22 The Harms of Medical School8:13 The Profit Mill in Centralized Medicine & Banks; Rockefeller Medicine & Fed Reserve; Flexnor Report; Big Harma (Pharma)14:21 The Role of Light in Life & Health; Isolated Blue Light is the new smoking17:09 Melanin20:13 Melanin's Role as an Antioxidant & Detoxing23:07 Autism & Sensitivities26:24 Melatonin's Additional Roles29:10 The Harms of Artificial Light on Health; POMC; Cortisol31:18 Artificial Light at Night & Sleep; Massive Hormone Disruptor33:21 The Electron Transport Chain & OXPHOS; Cytochromes; Biological Energy; ROS; Red Light & Cytochrome C Oxidase38:21 The Massive Scams of Heart Prescriptions, Guidelines, Cholesterol and Statins & a leading cause of death is still Heart Disease, Heart Attacks; Big Harma49:19 Environmental Factors & Modern Diseases53:55 Covert Push:Pull Tactic on Humans from Medicine & Health Insurance; The Profit Mills58:38 Autism & Lifestyle; Circadian Rhythms, Diet, & GI59:35 Daylight Computer Company, use "autism" for $50 discount1:03:00 Chroma Light Devices, use "autism" for 10% discountX: https://x.com/rps47586YT: https://www.youtube.com/channel/UCGxEzLKXkjppo3nqmpXpzuAemail: info.fromthespectrum@gmail.com

Today's episode is all about Autism and its associated communication disorders, as outlined in the DSM-5-TR, focusing on social communication disorder (SCD), childhood onset fluency disorder (stuttering), speech sound disorder, and developmental language disorder (DLD), which affect 50-70%, 4-22%, 20-30%, and up to 50% of Autistic individuals, respectively. We explore neural underpinnings, highlighting hypoactivation in brain regions and brain waves are discussed that are critical for social cognition, alongside disrupted connectivity in networks like the arcuate and superior longitudinal fasciculi. Two genes- FOXP2 and CNTNAP2 are also discussed.Other relevant episodes:Decoding the Brain: How Reading works in Autism and Dyslexia https://youtu.be/s1-7HZchy84?si=-r9foWP8Gmw-Wsx2Autism and Speech & Language https://youtu.be/jhAA-UWduKg?si=TfVWi9AfbFZgv8XVAutism and Sensory Processing part 2 https://youtu.be/iWy9Rligzic?si=2LATDK0bPl6jjat9Daylight Computer Companyuse "autism" for $50 off athttps://buy.daylightcomputer.com/autismChroma Light Devicesuse "autism" for 10% discount athttps://getchroma.co/?ref=autismCognity AI for Autistic Social Skillsuse "autism" for 10% discount athttps://thecognity.com00:00 - Introduction to Autism and Communication Disorders; DSM-5-TR, social communication, pragmatic deficits, stuttering, speech sound disorder, developmental language disorder04:02 - Brain Regions and Social Cognition; medial prefrontal cortex, temporal parietal junction, superior temporal sulcus, "theory of mind", hypoactivation06:01 - Autistic Phenotype and Neural Connectivity; Mirror neurons, sensory processing, under-connectivity, arcuate fasciculus, superior longitudinal fasciculus11:38 - Brainwave Patterns and Measurement Techniques; EEG, MEG, gamma band, alpha band suppression, fMRI, DTI & Factional Anisotropy16:27 - Genetic Contributions to Communication; FOXP2, CNTNAP2, neural circuits, synaptic plasticity, language processing19:56 - Social Communication Disorder (SCD); Overview pragmatic language, non-verbal cues, autism differentiation24:45 - Childhood Onset Fluency Disorder (Stuttering); basal ganglia, motor planning, rTMS, dopamine signaling, Go-Stop, Go-Stop, Go-Stop...30:05 - Speech Sound Disorder Speech; Broca’s area, superior temporal gyrus, articulation errors, PROMPT therapy35:25 - Developmental Language Disorder (DLD); Broca’s area, Wernicke’s area, language comprehension, early intervention40:56 - Importance of Early Intervention; speech therapy, neural connectivity, personalized interventions, neurofeedback.X: https://x.com/rps47586YT: https://www.youtube.com/channel/UCGxEzLKXkjppo3nqmpXpzuAemail: info.fromthespectrum@gmail.com

This week's episode is all about Reading. We will go through the entire process from the moment light hits the retina (50-100ms) to formulating speech (600ms or so). That is, either speaking out loud or silently speaking while reading, a phenomena called subvocalization. We do this when reading to the self. Either way, we speak while reading.We will compare so called normal readers, the Autistic phenotype, and dyslexia, and at times the odd contrasts of the Autistic phenotype AND dyslexia. Lots of neurobiology, measurement instruments, brain waves (oscillations, frequencies), however, I will hopefully provide easy to understand analogies.The entire reading process is covered.Daylight Computer Companyuse "autism" for $50 off athttps://buy.daylightcomputer.com/autismChroma Light Devicesuse "autism" for 10% discount athttps://getchroma.co/?ref=autismCognity AI for Autistic Social Skillsuse "autism" for 10% discount athttps://thecognity.com00:00 - Overview of reading process and neurobiology03:28 - Visual processing in V1 (primary visual cortex), V2-V4 (secondary visual cortex)4:42 - Neuroplasticity of Blind using V1-V4 for Braille07:17 - Neural oscillations (Delta, Theta, Alpha, Beta, Gamma)10:07 - Visual word form area (VWFA) recognizes patterns, begins sequencing letters & recognizes the word, Example: "d-o-g" & 'd' not 'b', 'o' not 'c,' 'g' not 'p.'13:01 - Phonological processing in temporal-parietal cortex15:54 - Fractional anisotropy (FA) & Diffusion Tensor Imaging (DTI) and arcuate fasciculus; Myelination, Water Flow, Garden Hose example18:06 - Detailed discussion of orthographic processing begins (VWFA’s role in recognizing visual word forms)21:26 - Detailed discussion of cerebellum’s role in eye movements begins (Purkinje cells and saccades)24:07 - Detailed discussion of spelling difficulties begins (orthographic processing challenges in autism/dyslexia)27:41 - Detailed discussion of semantic integration begins (delays in dyslexia, inferior frontal gyrus)30:55 - Detailed discussion of orthographic confusion begins (e.g., "except" vs. "expert")33:30 - Detailed discussion of phonological processing begins (temporal-parietal cortex mapping words to sounds)34:18 - Cerebellum mentioned regarding tongue movements (Purkinje cells refine timing for speech)36:10 - Subvocalization in silent reading37:07 - Oscillations in VWFA for autistic phenotype; Comprehension lags in Autism due to delayed N40039:19 Daylight Computer Company (and Daylight Kids !), use "autism" for $50 discount41:40 Chroma Light Devices, use "autism" for 10% discount44:52 Reviews/Ratings, Contact InfoX: https://x.com/rps47586YT: https://www.youtube.com/channel/UCGxEzLKXkjppo3nqmpXpzuAemail: info.fromthespectrum@gmail.com

Today's episode continues with visual thinking. We will learn more about the accelerated learning patterns with visual thinking and the Autistic phenotype. Autistic individuals create detailed mental "catalogs" of images and experiences, much like AI’s data processing. We explore Temple Grandin’s vivid descriptions of thinking in pictures, alongside early observations from Kanner (1943) and Asperger (1944), who noted autistic intelligence in their "little professors." The discussion covers weak central coherence theory & specific details drives exceptional learning but can complicate social interactions and broader contextual understanding.We will discuss the Autistic brain and machine learning, from pattern recognition to iterative refinement. Enhanced neural connections, like those linking the visual and frontal cortex, enable Autistic individuals to excel in tasks requiring precision, such as spotting subtle differences or memorizing facts. The episode contrasts this unique cognitive style with societal norms, advocating for embracing these strengths.Frith & Happe Weak Central Coherence https://link.springer.com/article/10.1007/s10803-005-0039-0Visual Thinking part 1: Neurobiology & Autistic's Intense Inner World https://youtu.be/XqQ8jCvWzYc?si=3cEIm1omi0JUAKSKDaylight Computer Companyuse "autism" for $50 off athttps://buy.daylightcomputer.com/autismChroma Light Devicesuse "autism" for 10% discount athttps://getchroma.co/?ref=autism00:00 - Introduction to Visual Thinking; "movies" in the mind, and its impact on learning.02:02 - Historical Context of Autism References to Leo Kanner (1943) and Hans Asperger (1944) highlight early observations of autistic intelligence, with terms like "little professors" and "autism" (from "autos," meaning self)04:01 - Social Norms vs. Autistic Phenotype The autistic cognitive style contrasts with societal expectations, which favor fitting individuals into predictable "boxes" for evaluation and acceptance, making social integration and education challenging for autistic individuals.06:01 - Cataloging and AI Parallels; mental catalogs & specific images or experiences, similar to AI & machine learning, catalogs for categories08:46 Weak Central Coherence Theory; local, detail-oriented processing over global integration, enabling strengths like spotting hidden shapes10:28 Enhanced Perceptual Functioning, visual and auditory domains, allowing precise cataloging of sensory details, tasks & precision.12:02 Anecdotal Person Comparison & Associative Learning15:30 Pattern Recognition and Detail Focus18:26 Types of Visual Thinkers20:36 Neural Connectivity23:22 Perceptual Learning and Neuroplasticity; Accelerated learning27:04 AI and Autistic Brain Similarities33:35 Daylight Computer Company (and Daylight Kids !), use "autism" for $50 discount35:53 Chroma Light Devices, use "autism" for 10% discount38:59 Don't underestimate this Autistic Phenotype.X: https://x.com/rps47586YT: https://www.youtube.com/channel/UCGxEzLKXkjppo3nqmpXpzuAemail: info.fromthespectrum@gmail.com

Today's episode is all about visual thinking. We will explore vivid mental imagery and sensory processing. We will cover why Autistic individuals process detailed "pictures and movies" in the mind, exemplified by an anecdote of visualizing oak tree bark with tactile detail. Sensory challenges are highlighted, with a Bee Movie analogy illustrating the intense, efficient visual input. The Autistic sensory journey is described as fast but rocky, contrasting with non-autistic processing. Hyperconnectivity in visual pathways amplifies detail-oriented cognition, often leading to sensory overload.The episode explains how retinal ganglion cells and visual cortex hyperactivity enhance imagery in Autism. Kanner and Asperger’s observations underscore visual memory strengths and technical interests, like pattern recognition. Increased mini-column density and reduced inhibition boost local processing but risk overload. Temple Grandin’s insights show visual thinking’s strengths in tasks like designing animal pathways, though social tasks challenge due to weaker prefrontal connectivity. The Autistic brain’s wiring is framed as a unique strength, fostering intense, detailed cognitionTemple Grandin https://www.templegrandin.com/templegrandinbooks.htmlSensory Processing part 1 https://youtu.be/HTnFm8nY4oY?si=4Xso_tI_hMwhY_SXSensory Processing part 2 https://youtu.be/n31gyLb4ddM?si=CouaBhiVm8KixtG-Supplementing Relationships part 1 https://youtu.be/lglEGQ7pSlc?si=ncpla784LxOyUcQcSupplementing Relationships part 2 https://youtu.be/W8E2B7Qu4mg?si=UJE850SwvPmtOmEkDaylight Computer Companyuse "autism" for $50 off athttps://buy.daylightcomputer.com/autismChroma Light Devicesuse "autism" for 10% discount athttps://getchroma.co/?ref=autism00:00 Introduction to Visual Thinking02:00 Anecdote: Oak Tree Visualization; tree bark, tactile05:50 Sensory Processing Challenges; overload, information rate, avoidance09:40 Anecdote: Bee Movie Analogy; synchronized, intense, fast13:30 Autistic Sensory Rates/Speeds17:20 Eye Biology and Neural Relays; Retinal ganglion, SHANK3; Building Models details-to-general21:10 Magnocellular vs. Parvocellular Pathways; Motion, color, glutamate, GABA signaling25:00 Visual Cortex Hyperactivity; V1-V4, fMRI, synaptic pruning, details28:50 Mini-Columns and Sensory Overload; Neural units, inhibition, dense connections32:40 Kanner and Asperger Insights; Social isolation, technical interests, patterns38:39 Daylight Computer Company (and Daylight KIDS !), use "autism" for $50 discount40:54 Chroma Light Devices, use "autism" for 10% discount44:07 Reviews/Ratings & Contact InfoX: https://x.com/rps47586YT: https://www.youtube.com/channel/UCGxEzLKXkjppo3nqmpXpzuAemail: info.fromthespectrum@gmail.com