Discover2DocsToc050. Premenstrual Dysphoric Disorder, and How to Distinguish it from PMS, with Ladan Hariri, MD
050. Premenstrual Dysphoric Disorder, and How to Distinguish it from PMS, with Ladan Hariri, MD

050. Premenstrual Dysphoric Disorder, and How to Distinguish it from PMS, with Ladan Hariri, MD

Update: 2025-11-17
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Imagine living only one good week out of every month, feeling misunderstood, and struggling with extreme mood swings that disrupt your entire life. This episode sheds light on PMDD, a condition often mislabeled as PMS, offering validation and practical ways to reclaim those lost weeks.

00:00 Introduction to PMDD
02:37 PMS vs. PMDD: Key Differences
06:00 Debilitating Symptoms & Misdiagnosis
09:38 Understanding PMDD Mechanism & Endometriosis
12:55 Treatment & Nutritional Support
17:46 Support Systems & Technology’s Role
22:53 Future Outlook and Living with PMDD
25:52 AI in Medicine: Opportunities & Fears
31:42 Final Thoughts & Finding Support


  • “PMS is kind of like the annoying friend or the annoying cousin that comes and visits you once a month… versus PMDD who is perhaps a very, very toxic friend.”
  • “PMS is uncomfortable. PMDD is debilitating.”
  • “Doctor, I only get one good week out of every month. That’s 25% on average, right?”


This episode marks a significant milestone for 2DocsToc, reaching its 50th episode with the return of Dr. Hariri. The discussion highlights the historical lack of awareness for women’s health issues like PMDD, comparing it to past dialogues around breast cancer awareness. Rob notes the common dismissal of these symptoms by medical professionals, underscoring the importance of increased understanding and empathy.


Get In Touch!

rob@2docstocpodcast.com

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050. Premenstrual Dysphoric Disorder, and How to Distinguish it from PMS, with Ladan Hariri, MD

050. Premenstrual Dysphoric Disorder, and How to Distinguish it from PMS, with Ladan Hariri, MD

Abbass Shafii, MD and Rob Hoyer, MD