#140: How Real-World Evidence Is Shaping the Future of Multiple Sclerosis Treatment – Highlights from ECTRIMS 2025
Description
In this episode, I take you behind the scenes of ECTRIMS 2025 and explore seven fascinating studies that show how multiple sclerosis (MS) care is evolving — from safety monitoring and infection risks to data-driven, personalized treatment decisions.
You'll learn about:
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How often late-onset neutropenia occurs in people on Rituximab and who's most at risk.
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What factors increase the chance of serious infections with Ocrelizumab.
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Why early high-efficacy treatment leads to better long-term outcomes across four countries.
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What happens to memory B cells during long-term Ocrelizumab therapy and what that means for extended dosing intervals.
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What the FAERS database tells us about tumor signals and why HPV vaccination remains essential for women with MS.
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How real-world data from the TEMPOS study (France) reveal a massive shift toward anti-CD20 therapies — especially Ofatumumab.
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And finally, how a new AI-based prediction tool helps estimate individual risk when stopping a DMT.
🎯 Main takeaway: MS treatment is moving toward earlier, stronger, and more personalized approaches — guided by real-world evidence and smart technology.
👉 You can read the full article with all study details, numbers, and takeaways here: https://ms-perspektive.de/en/140-ectrims-rwe
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See you soon and try to make the best out of your life,
Nele
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