Clinical Pearls from Dr. Dominic D'Agostino: Therapeutic Strategies and Clinical Success with the Ketogenic Diet 

For this week’s episode of the Clinician’s Corner, we’re doing something differently. We have gone into the archives and pulled out clinical pearls from some of our favorite episodes, and we’re starting today with one of our most popular interviews with Dr. Dominic D’Agostino - where we unpack the ketogenic diet in all its nuances.

 

This interview first aired back in 2023, and the full interview can be viewed here. 

 

Clinical pearls we extracted from the original interview:

When the ketogenic diet is best used clinically; when it’s contraindicated; and how to structure it for best results

What the latest research is telling us about therapeutic application of this protocol - from metabolic health to neurological considerations and cancer 

Exogenous ketones: when and how to use them 

The intricacies of macronutrient ratios and when/how to cycle in and out of ketosis

Measurement: the best forms for tracking ketosis and other key biomarkers to monitor

 

The Clinician’s Corner is brought to you by Restorative Wellness Solutions. 

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Connect with Dr. D’Agostino:

Website: https://drdominicdagostino.com/

Instagram:  https://www.instagram.com/dominic.dagostino.kt/   

LinkedIn:  https://www.linkedin.com/in/dominic-d-agostino-156014b/
Twitter:  https://twitter.com/DominicDAgosti2   

 

Learn more about the ketogenic diet here: https://ketonutrition.org/ 

 

Timestamps: 

00:00 History and Uses of Ketogenic Diet

06:25 Liver's Role in Ketone Production

07:22 Preventing Kidney Stones on Keto

13:15 Ketogenic Diet Supplement Tips

14:58 Minimal Supplements for Ketogenic Diet

18:07 Misleading Marketing of 1,3-Butanediol

24:08 Advanced Hormone and Metabolomics Testing

27:20 Monitor Meds During Diet Changes

Speaker bio:

 

Dr. D’Agostino is a tenured Associate Professor at the University of South Florida (USF) Morsani College of Medicine in the Department of Molecular Pharmacology and Physiology. He teaches medical neuroscience, medical physiology, nutrition and neuropharmacology. He is also a Research Scientist at the Institute for Human and Machine Cognition (IHMC) to assist with their efforts towards optimizing the safety, health and resilience of the warfighter and astronaut. His primary research focuses on developing and testing nutritional and metabolic-based therapies for a variety of disease states and advancing the use of metabolic-based therapies into human clinical applications.

 

Keywords: 

ketogenic diet, therapeutic ketosis, blood ketone levels, exogenous ketones, metabolic therapies, epilepsy, neuroprotection, anti-seizure strategy, type 2 diabetes, weight loss, cancer, muscle wasting, Parkinson’s disease, Alzheimer’s disease, migraines, polycystic ovary syndrome, psychiatric disorders, bipolar disorder, anxiety, autism, traumatic brain injury, non-alcoholic fatty liver disease, stroke, GLUT1 deficiency, carnitine supplementation, kidney stones, electrolyte balance, MCT oil, creatine monohydrate, caffeine and ketone production, comprehensive blood work

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