Acute Rheumatic Fever: High-Yield USMLE Topics You Must Know!
Update: 2025-05-08
Description
ARF is an immune-mediated sequela of untreated strep pharyngitis and a must-know topic for USMLE Step 1.
🔬 Key Concepts:
• J♥NES criteria – Major clinical features you can’t forget
• Type II hypersensitivity (molecular mimicry)
• Mitral valve involvement: regurgitation early, stenosis later
• Penicillin for treatment and prophylaxis
🧠Memorize the criteria, recognize the cardiac complications, and understand the immune mechanism behind it all.
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