This article "Atomically accurate de novo design of antibodies with RFdiffusion" is published in Nature.

Author: Nathaniel R. Bennett

Journal: Nature

Year: 2025

Podcast type: Short

The authors are:

Nathaniel R. Bennett

Joseph L. Watson

Robert J. Ragotte

Andrew J. Borst

DéJenaé L. See

Connor Weidle

Riti Biswas

Yutong Yu

Ellen L. Shrock

Russell Ault

Philip J. Y. Leung

Buwei Huang

Inna Goreshnik

John Tam

Kenneth D. Carr

Benedikt Singer

Cameron Criswell

Basile I. M. Wicky

Dionne Vafeado

Mariana Garcia Sanchez

Ho Min Kim

Susana Vázquez Torres

Shirley M. Sun

Timothy T. Spear

Yi Sun

Keelan O’Reilly

John M. Maris

Nikolaos G. Sgourakis

Roman A. Melnyk

Chang C. Liu

David Baker

Affiliations:

Nathaniel R. Bennett, Joseph L. Watson, Robert J. Ragotte, Andrew J. Borst, DéJenaé L. See, Connor Weidle, Ellen L. Shrock, Philip J. Y. Leung, Buwei Huang, Inna Goreshnik, Kenneth D. Carr, Benedikt Singer, Cameron Criswell, Basile I. M. Wicky, Dionne Vafeados, Mariana Garcia Sanchez, Susana Vázquez Torres ,Department of Biochemistry, University of Washington, Seattle, WA, USA

Nathaniel R. Bennett, Joseph L. Watson, Robert J. Ragotte, Andrew J. Borst, DéJenaé L. See, Connor Weidle, Ellen L. Shrock, Philip J. Y. Leung, Buwei Huang, Kiril Goreshnik, Cameron Criswell, Dionne Vafeados, Mariana Garcia Sanchez, Susana Vázquez Torres ,Institute for Protein Design, University of Washington, Seattle, WA, USA

Nathaniel R. Bennett, Riti Biswas ,Graduate Program in Molecular Engineering, University of Washington, Seattle, WA, USA

DéJenaé L. See, Buwei Huang ,Department of Bioengineering, University of Washington, Seattle, WA, USA

Yutong Yu, Chang C. Liu ,Department of Biomedical Engineering, University of California, Irvine, CA, USA ,Center for Synthetic Biology, University of California, Irvine, CA, USA

Yutong Yu, Department of Pharmaceutical Sciences, University of California, Irvine, CA, USA

Russell Ault, John M. Maris ,Department of Pediatrics, Children’s Hospital of Philadelphia, Philadelphia, PA, USA ,Department of Pediatrics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA

Inna Goreshnik, David Baker ,Howard Hughes Medical Institute, University of Washington, Seattle, WA, USA

John Tam, Roman A. Melnyk ,Molecular Medicine Program, The Hospital for Sick Children, Toronto, Ontario, Canada

Ho Min Kim ,Center for Biomolecular and Cellular Structure, Institute for Basic Science (IBS), Daejeon, Republic of Korea , Department of Biological Sciences, KAIST, Daejeon, Republic of Korea

Susana Vázquez Torre, Graduate Program in Biological Physics, Structure and Design, University of Washington, Seattle, WA, US

Shirley M. Sun, Nikolaos G. Sgourakis

Center for Computational and Genomic Medicine, Department of Pathology and Laboratory Medicine, Children’s Hospital of Philadelphia, Philadelphia, PA, USA, Department of Biochemistry and Biophysics, University of Pennsylvania, Philadelphia, PA, USA

Timothy T. Spear, Keelan O’Reilly, Division of Oncology and Center for Childhood Cancer Research, Children’s Hospital of Philadelphia, Philadelphia, PA, USA

Roman A. Melnyk, Department of Biochemistry, University of Toronto, Toronto, Ontario, Canada

Chang C. Liu, Department of Chemistry, University of California, Irvine, CA, USA, Department of Molecular Biology & Biochemistry, University of California, Irvine, CA, USA