DiscoverDemy-Colton Talks BiotechDrugging the UnDruggable
Drugging the UnDruggable

Drugging the UnDruggable

Update: 2025-08-25
Share

Description

Up to 85% of the human proteome is considered “undruggable,” with proteins that lack the pockets where traditional therapeutics can bind. But that barrier is beginning to shift.

A new wave of biotech companies is bringing forward breakthrough technologies designed to target the most elusive proteins—opening the door to therapies once thought impossible. In this episode, we explore the science, innovation, and opportunities behind cracking the code of the so-called “undruggable” proteome.

Comments 
00:00
00:00
x

0.5x

0.8x

1.0x

1.25x

1.5x

2.0x

3.0x

Sleep Timer

Off

End of Episode

5 Minutes

10 Minutes

15 Minutes

30 Minutes

45 Minutes

60 Minutes

120 Minutes

Drugging the UnDruggable

Drugging the UnDruggable

Demy-Colton