DiscoverProteomics in ProximityEmpowering breast cancer proteomics with genomics with Dr. Jochen Schwenk
Empowering breast cancer proteomics with genomics with Dr. Jochen Schwenk

Empowering breast cancer proteomics with genomics with Dr. Jochen Schwenk

Update: 2023-05-31
Share

Description

Welcome to Olink Proteomics in Proximity Podcast! 
 

Below are some useful resources from this episode: 
 

Highlighted pre-print article: Malarstig A, Grassman F, Dahl L, et al. Evaluation of Circulating Plasma Proteins in Breast Cancer: A Mendelian Randomization Analysis. ResearchSquare 2023.04.04. DOI: https://doi.org/10.21203/rs.3.rs-2749047/v1

 

Highlighted platform that was used to measure proteins in this study with a next-generation sequencing (NGS) readout (Olink® Explore 3072): https://olink.com/products-services/explore/

 
 

Learn more about the consortiums or cohorts mentioned in the podcast:

 

UK Biobank Pharma Proteomics Project (UKB-PPP) is currently performing one of the world’s largest scientific studies of blood protein biomarkers conducted to date: https://www.ukbiobank.ac.uk/learn-more-about-uk-biobank/news/uk-biobank-launches-one-of-the-largest-scientific-studies 

 

Human Proteome Atlas (HPA) aims to map all human proteins using various omics technologies: https://www.proteinatlas.org/ 

 

SCALLOP consortium is a collaborative framework for discovery and follow-up of genetic associations with proteins on the Olink Proteomics platform: https://olink.com/our-community/scallop/ 

 

KARMA cohort is a prospective screening cohort for breast cancer in Sweden: https://karmastudy.org/ongoing-research/the-karma-cohort/ 

 

Swedish Twin Registry (referred as “Twin Gene cohort” in the podcast) is the largest of its kind, containing genetic information about ~87,000 twin pairs: https://ki.se/en/research/the-swedish-twin-registry 

 

 

Additional published articles and books mentioned during the podcast:

 

Hood, Leroy and Price, Nathan. The Age of Scientific Wellness: Why the Future of Medicine Is Personalized, Predictive, Data-Rich, and in Your Hands, Cambridge, MA and London, England: Harvard University Press, 2023. https://doi.org/10.4159/9780674293465

 

Suhre K, McCarthy MI, Schwenk JM. Genetics meets proteomics: perspectives for large population-based studies. Nat Rev Genet. 2021 Jan;22(1):19-37. doi: 10.1038/s41576-020-0268-2. Epub 2020 Aug 28. PMID: 32860016. https://pubmed.ncbi.nlm.nih.gov/32860016/

 

 

Would you like to subscribe to the podcast on your favorite player or app? You can do so here: 

Apple Podcasts: https://apple.co/3T0YbSm 
 

Spotify Podcasts: https://open.spotify.com/show/2sZ2wxO... 
 

Google Podcasts: https://podcasts.google.com/feed/aHR0... 
 

Amazon Music: https://music.amazon.com/podcasts/d97... 
 

Podcast Addict: https://podcastaddict.com/podcast/409... 
 

Deezer:

Comments 
loading
00:00
00:00
1.0x

0.5x

0.8x

1.0x

1.25x

1.5x

2.0x

3.0x

Sleep Timer

Off

End of Episode

5 Minutes

10 Minutes

15 Minutes

30 Minutes

45 Minutes

60 Minutes

120 Minutes

Empowering breast cancer proteomics with genomics with Dr. Jochen Schwenk

Empowering breast cancer proteomics with genomics with Dr. Jochen Schwenk

Olink Proteomics