Ep. 279: “Direct Reprogramming” Featuring Dr. Samantha Morris
Description
Guest:
Dr. Samantha Morris is an Associate Professor of Medicine at Brigham and Women’s Hospital and Associate Professor of Systems Biology at Harvard Medical School. She talks about dissecting and manipulating the genetic pathways that regulate cell identity. She discusses tools to measure cell fate transitions and incorporating in silico and in vitro experiments.
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The Stem Cell Science Round Up
A Prenatal Skin Atlas – A skin atlas revealed that crosstalk between non-immune and immune cells underpins the formation of hair follicles.
Human Pancreatic Differentiation – Researchers used single-nucleus RNA sequencing to characterize the human fetal pancreatic microenvironment.
A Cardiac Fibrosis Therapeutic Target – High-throughput screening in iPSC-derived cardiac fibroblasts identified MD2 as a therapeutic target for cardiac fibrosis.
Mammalian Gastrulation – Scientists identified a link between the pathways that produce energy for embryo growth and the systems that regulate cell specialization.
Image courtesy of Dr. Samantha Morris
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