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Tags: Neurology, Pediatrics

Show Notes

Introduction

• The episode focuses on ataxia in children, which can range from self-limiting to life-threatening conditions.


• Pediatric emergency medicine specialist shares insights on the topic.

The Case

• An 18-month-old boy presented with ataxia, unable to keep his head up, sit, or stand, and began vomiting.


• Previously healthy except for recurrent otitis media and viral-induced wheezing.


• The decision to take the child to the emergency department (ED) was based on acute symptoms.

Differential Diagnosis

• Common causes include acute cerebellar ataxia, drug ingestion, Guillain-Barre syndrome, and basilar migraine.


• Less common causes include cerebellitis, encephalitis, brain tumors, and labyrinthitis.

Importance of History and Physical Examination

• A detailed history and physical exam are essential in diagnosing ataxia.


• Key factors include time course, recent infections, signs of increased intracranial pressure, and toxic exposures.


• Look for signs such as bradycardia, hypertension, vomiting, and overall appearance.

Diagnostic Workup

• Initial tests include point-of-care glucose and neuroimaging for concerns about trauma or increased intracranial pressure.


• MRI is preferred for posterior fossa abnormalities, but non-contrast head CT is commonly used due to accessibility.


• Lumbar puncture may be needed if meningismus is present.

Treatment Approach

• Treatment depends on the underlying cause:
  
  
  
  • Acute cerebellar ataxia is self-limiting and typically resolves with time.
  
  
  • Antibiotics are required for meningitis or encephalitis.
  
  
  • Steroids may be useful for cerebellitis and acute disseminated encephalomyelitis (ADEM).
  
  
  • Specialist consultations are necessary for severe diagnoses like intracranial masses.
  
  
  
  

Outcome of the Case Study

• The child had a normal fast T2 MRI and improved during the ED stay.


• Diagnosed with a combination of cerebellar ataxia and labyrinthitis.


• Received myringotomy tubes and experienced no further neurologic changes or otitis media episodes.

Take-Home Points

1. Diverse Etiologies:  Ataxia in children can have various causes that range from self-limiting to life-threatening


2. Comprehensive Assessment: History and physical exams guide diagnosis and workup direction, focusing on symptom time course, infections, and toxic exposures.


3. Physical Examination Clues: Vital signs and appearance offer clues; increased ICP may present with bradycardia, hypertension, and vomiting.


4. Diagnostic Imaging: Point-of-care glucose testing and neuroimaging are key; MRI is preferred for posterior fossa abnormalities.


5. Tailored Treatment: Treatment varies by cause; acute cerebellar ataxia typically resolves over time without specific intervention.