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Eric Topol: The Keys to Healthy Aging

Eric Topol: The Keys to Healthy Aging

Update: 2025-09-11
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Howie and Harlan are joined by physician, scientist, and author Eric Topol to discuss his new book, Super Agers: An Evidence-Based Approach to Longevity; the potential of individualized polygenic risk scores; and the dangers of the protein craze.

Links:

Health & Veritas Ep. 58: Dr. Eric Topol: Pushing Medicine into the Future

Eric Topol: Super Agers: An Evidence-Based Approach to Longevity

Eric Topol: “The Drivers of Age-Related Diseases”

Eric Topol: “A Review of Outlive

Eric Topol, Ground Truths podcast: “Peter Attia: Our conversation about his hit book Outlive, Medicine 3.0, promoting healthspan, GLP-1 drugs and more”

Eric Topol: The Creative Destruction of Medicine

Eric Topol: The Patient Will See You Now

Eric Topol: Deep Medicine

Eric Topol: “Our Preoccupation With Protein Intake”

The Daily podcast: “How America Got Obsessed with Protein”

“High-protein diets increase cardiovascular risk by activating macrophage mTOR to suppress mitophagy”

“Identification of a leucine-mediated threshold effect governing macrophage mTOR signalling and cardiovascular risk”

“5 Takeaways From Kennedy’s Senate Hearing”

Eric Topol on the Dr. Hyman Show: “How AI Could Change Your Next Doctor Visit Forever!”

Eric Topol: “The Business of Promoting Longevity and Healthspan”

The Age of the Infovore: Succeeding in the Information Economy

Eric Topol, Ground Truths podcast: “Tyler Cowen: The Prototypic Polymath”

“How a scientist who studies ‘super agers’ exercises for a longer life”

Eric Topol: “Our Sleep, Brain Aging, and Waste Clearance”

“Alzheimer's genes: Are you at risk?”

Eric Topol: “The Breakthrough Blood Test for Alzheimer's Disease”

Eric Topol: “Predicting and preventing Alzheimer’s disease”

Eric Topol: “The personal and clinical utility of polygenic risk scores”

Eric Topol: “Polygenic Risk Scores: Ready for Prime Time?”

“Physical Activity Among Adults Aged 18 and Over: United States, 2020”

“Wellderly” studies

Eric Topol: “What My Two 98-Year-Old Patients Taught Me About Longevity”

Eric Topol, Ground Truths podcast: “Mike Osterholm & Eric Topol Discuss The Big One book”

“Hypertrophic Cardiomyopathy”

Eric Topol: “Lithium and Its Potential Protection from Alzheimer's Disease”

Eric Topol: “High-performance medicine: the convergence of human and artificial intelligence”


Learn more about the MBA for Executives program at Yale SOM.

Email Howie and Harlan comments or questions.

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Eric Topol: The Keys to Healthy Aging

Eric Topol: The Keys to Healthy Aging