Exploring How Social Stress Ages Cells: P53 and Senescence Connection 040
Description
In this episode of the RevGenetics Podcast, Les and Amy explore a profound connection between our environment and our DNA: how social stressors impact cellular biology. We delve into the "p53-dependent cellular senescence" pathway to understand how social adversity can physically accelerate the aging process.
Using a "factory analogy," we explain how damaged cells are forced into retirement to prevent serious issues like cancer. However, when these retired cells accumulate due to chronic stress, they trigger inflammation and faster aging. p53 acts as the cell’s ultimate damage inspector, deciding when a cell should stay in the workforce or retire permanently. Join us as we unpack how social factors influence biological aging at a molecular level and what this means for the future of public health.
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Referenced Study:
🔗 Current Understanding of p53-Dependent Cellular Senescence in Health Disparities: Molecular Insights and Public-Health Strategies
Hashtags:
#RevGenetics #Longevity #CellularSenescence #p53 #BiologicalAging #SocialStress #HealthyAging #DNAIntegrity #PublicHealth #SciencePodcast #AgingResearch #MolecularBiology #HealthDisparities #CellularHealth #AgingScience #Biotechnology #AntiAging #StressResearch #LongevityLifestyle #Epigenetics
United States
