Preventative Approaches to Aging: Harnessing Geroprotectors for Longevity 034
Description
In this episode of the RevGenetics Podcast, Les and Amy explore a monumental shift in medical philosophy: treating aging itself as the root cause of chronic disease. We delve into the cutting-edge science of preventative care, focusing on the "hallmarks of aging" like cellular senescence and epigenetic alterations to understand how we can stay healthier for longer.
We break down how new interventions aim to clear out "zombie cells" and fix DNA management issues that lead to systemic decline. While lifestyle changes are essential, the conversation shifts to the frontier of geroprotectors—natural compounds and drugs designed to target underlying biological markers. Specifically, we look at recent research into histone deacetylase (HDAC) inhibitors and their potential to extend chronological lifespan by addressing the root causes of aging.
Join us as we unpack the implications of this new approach and what it means for the future of longevity and overall health.
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Referenced Study:
🔗 Combinations of histone deacetylase inhibitors extend chronological lifespan in S. cerevisiae
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