Exploring the Link Between Inflammatory Bowel Disease and Dementia
Update: 2025-09-26
Description
- People with dementia who develop inflammatory bowel disease (IBD) show faster deterioration in thinking, memory, and reasoning skills
- A large-scale analysis of 7.9 million participants revealed IBD patients face significantly elevated dementia risk, with Crohn's disease showing stronger association than ulcerative colitis
- IBD triggers systemic inflammation, releasing cytokines that breach the blood-brain barrier, disrupting neural communication and contributing to progressive neurodegeneration over time
- IBD creates gut dysbiosis, producing neurotoxic metabolites, and increasing intestinal permeability, allowing harmful substances to reach the brain through bloodstream circulation
- Supporting cellular health through vegetable oil elimination, proper carbohydrates, targeted probiotics, vitamin D optimization, and natural antimicrobials can address IBD's root causes
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